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Cell Biology Antibodies 2 Anti-Syndecan-1/CD138 Antibody CAB1235
Key Features

CD138/Syndecan-1 Rabbit Polyclonal Antibody (CAB1235)

Datasheet MSDS
SKU CAB1235
Product Type Antibody
Antibody Type Polyclonal Antibody
Reactivity Human, Mouse
Host Species Rabbit
Synonyms SDC, CD138, SYND1, syndecan, CD138/Syndecan-1
Research Use Cell Biology
€96 - €370

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Description

system_update_altDatasheetsystem_update_altMSDS

CD138/Syndecan-1 Antibody (CAB1235)

The CD138/Syndecan-1 Antibody (CAB1235) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot and immunohistochemistry applications.Syndecan-1 is known to play a role in various physiological and pathological processes, including wound healing, inflammation, and cancer progression. By targeting Syndecan-1 with this antibody, researchers can accurately detect and analyze the protein in different cell types, providing valuable insights into its function and potential as a therapeutic target.

This antibody is validated for use in WB, IHC-P, ELISA applications and has demonstrated reactivity against Human, Mouse samples.

Product Name:CD138/Syndecan-1 Antibody
SKU:CAB1235
Size:20μL, 100μL
Reactivity:Human, Mouse
Conjugate:Unconjugated
Immunogen:Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Sequence:VATN LPPE DQDG SGDD SDNF SGSG AGAL QDIT LSQQ TPST WKDT QLLT AIPT SPEP TGLE ATAA STST LPAG EGPK EGEA VVLP EVEP GLTA REQE ATPR PRET TQLP TTHL ASTT TATT AQEP ATSH PHRD MQPG HHET STPA GPSQ ADLH TPHT EDGG PSAT ERAA EDGA SSQL PAAE GSGE QDFT FETS GENT AVVA VEPD RRNQ SPVD QGAT
Tested Applications:WB IHC-P ELISA
Recommended Dilution:
WB1:500 - 1:2000
IHC-P1:50 - 1:200
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:SDC, CD138, SYND1, syndecan, CD138/Syndecan-1
Positive Sample:U266, Mouse liver
Cellular Localization:Membrane, Secreted, Single-Pass Type I Membrane Protein.
Calculated MW:32kDa
Observed MW:32kDa/96kDa

The protein encoded by this gene is a transmembrane (type I) heparan sulfate proteoglycan and is a member of the syndecan proteoglycan family. The syndecans mediate cell binding, cell signaling, and cytoskeletal organization and syndecan receptors are required for internalization of the HIV-1 tat protein. The syndecan-1 protein functions as an integral membrane protein and participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. Altered syndecan-1 expression has been detected in several different tumor types. While several transcript variants may exist for this gene, the full-length natures of only two have been described to date. These two represent the major variants of this gene and encode the same protein.

Purification MethodAffinity purification
Gene ID6382
RRIDAB_2759193
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates, using CD138/Syndecan-1 Rabbit pAb (CAB1235) at 1:500 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
Product ImageImmunohistochemistry analysis of paraffin-embedded Human esophageal cancer using CD138/Syndecan-1 Rabbit pAb (CAB1235) at dilution of 1:100 (40x lens). High pressure antigen retrieval performed with 0.01M Citrate buffer (pH 6.0) prior to IHC staining.
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