Description
Tarextumab ELISA Kit
The Tarextumab ELISA Kit (SKU: GXEL00263) enables sensitive, reproducible quantitative detection of Tarextumab in Plasma, Serum using a quantitative ELISA format. The assay delivers a detection range of 0.31-5 μg/mL and a sensitivity of 0.156 μg/ml and is read colorimetrically at 450 nm, making it well suited to quantitative research workflows.
Tarextumab, is a fully human mAb that inhibits ligand-dependent signaling through both Notch2 and Notch3. Tarextumab was tested in a range of xenograft models and found to be active in breast, ovarian, lung, and pancreatic tumors. Administration of tarextumab delayed tumor recurrence after chemotherapeutic treatment and reduced tumor-initiating cell frequency, particularly in combination with chemotherapy. Mechanism of action studies indicated that tarextumab blocked Notch signaling in both tumor and stromal cells and induced differentiation of tumor cells. In the stromal cells, tarextumab inhibited gene expression required for the function of pericytes, vascular support cells essential for tumor angiogenesis.
Supplied with pre-coated microplates and all core reagents, the Tarextumab ELISA Kit gives you a validated, ready-to-use solution for Tarextumab research. Get accurate and reliable results with the Tarextumab ELISA Kit from Assay Genie.
| Product Name: | Tarextumab ELISA Kit |
| SKU: | GXEL00263 |
| Alternative Names: | OMP-59R5, 1359940-55-8 |
| Assay Type: | Quantitative |
| Detection Method: | Colorimetric |
| Sensitivity: | 0.156 μg/ml |
| Range: | 0.31-5 μg/mL |
| Sample Type: | Plasma, Serum |
| Storage: | 2-8°C. See Storage & Stability for details. |
| Note: | For Research Use Only. Not for diagnostic procedures. |
| Parameter | Specification |
|---|---|
| Assay Type | Quantitative |
| Detection Method | Colorimetric |
| Sensitivity | 0.156 μg/ml |
| Detection Range | 0.31-5 μg/mL |
| Recovery | 80-120% |
| Sample Types | Plasma, Serum |
The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.
Store the kit at 2-8°C on receipt. Avoid repeated freeze-thaw cycles.
