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TEC Rabbit Polyclonal Antibody (CAB0189)

SKU:
CAB0189
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Immunology
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:TEC Rabbit Polyclonal Antibody
SKU:CAB0189
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human Tec (NP_003206.2).
Sequence:MNFN TILE EILI KRSQ QKKK TSPL NYKE RLFV LTKS MLTY YEGR AEKK YRKG FIDV SKIK CVEI VKND DGVI PCQN KYPF QVVH DANT LYIF APSP QSRD LWVK KLKE EIKN NNNI MIKY HPKF WTDG SYQC CRQT EKLA PGCE KYNL FESS IRKA LPPA PETK KRRP PPPI PLEE EDNS EEIV VAMY DFQA AEGH DLRL ERGQ EYLI LEKN DVHW WRAR DKYG NEGY IPSN YVTG KKSN NLDQ YEWY CRNM NRSK AEQL LRSE DKEG GFMV RDSS QPGL
Tested Applications:WB IHC-P IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200
Synonyms:PSCTK4; Tec
Positive Sample:Jurkat,Mouse liver,Mouse spleen,Mouse kidney,Rat liver
Conjugate:Unconjugated
Cellular Localization:Cell membrane, Cytoplasm, Peripheral membrane protein, cytoskeleton.
Calculated MW:74kDa
Observed MW:68kDa

The protein encoded by this gene belongs to the Tec family of non-receptor protein-tyrosine kinases containing a pleckstrin homology domain. Tec family kinases are involved in the intracellular signaling mechanisms of cytokine receptors, lymphocyte surface antigens, heterotrimeric G-protein coupled receptors, and integrin molecules. They are also key players in the regulation of the immune functions. Tec kinase is an integral component of T cell signaling and has a distinct role in T cell activation. This gene may be associated with myelodysplastic syndrome.

Purification Method:Affinity purification
Gene ID:7006
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using Tec Rabbit pAb (CAB0189) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.DeTection: ECL Basic Kit (AbGn00020).Exposure time: 90s.

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