Teriparatide (Research-Grade) is a research-grade biosimilar monoclonal antibody targeting Parathyroid hormone. Reactivity: Human. Supplied as a liquid in 0.01M PBS pH 7.4. Applications: ELISA, functional assays and in vivo research. Endotoxin: < 10 EU/mg. Purity: >95% as determined by HPLC. For research use only.
Teriparatide is a portion of human parathyroid hormone (PTH), amino acid sequence 1 through 34, of the complete molecule (containing 84 amino acids). Endogenous PTH is the primary regulator of calcium and phosphate metabolism in bone and kidney. PTH increases serum calcium, partially accomplishing this by increasing bone resorption. Thus, chronically elevated PTH will deplete bone stores. However, intermittent exposure to PTH will activate osteoblasts more than osteoclasts. Thus, once-daily injections of teriparatide have a net effect of stimulating new bone formation leading to increased bone mineral density. _x000D_ • Parathyroid hormone and its related peptides in bone metabolism., PMID:34224692 _x000D_ • Parathyroid hormone (PTH) regulation of metabolic homeostasis: An old dog teaches us new tricks., PMID:35338013 _x000D_ • MicroRNAs in parathyroid physiopathology., PMID:27816765 _x000D_ • Parathyroid hormone treatment partially reverses endplate remodeling and attenuates low back pain in animal models of spine degeneration., PMID:37967203 _x000D_ • PTH and cardiovascular risk., PMID:32192791 _x000D_ • Parathyromatosis., PMID:23128122 _x000D_ • Nephrogenic calcific arteriopathy., PMID:22143475 _x000D_ • Hypoparathyroidism and pseudohypoparathyroidism., PMID:17117292 _x000D_ • Structural pharmacology of PTH and PTHrP., PMID:35953106 _x000D_ • Parathyroid hormone for bone regeneration., PMID:29926970 _x000D_
Product Name:
Teriparatide (Research-Grade)
SKU:
GXBS02474
Size:
100 µg, 1 mg
Antibody Type:
Monoclonal Antibody
Target:
Parathyroid hormone
Isotype:
Biosynthetic Parathyroid hormone (PTH) analogs.
Reactivity:
Human
Applications:
ELISA, Functional assay, Research in vivo
Synonyms:
52232-67-4
Recommended Dilutions:
ELISA: 1:2000-1:20000
Purity:
>95% as determined by HPLC.
Endotoxin Level:
< 10 EU/mg
Formulation:
0.01M PBS pH 7.4
State of Matter:
Liquid
Regulatory Status:
For research use only. Not suitable for clinical or therapeutic use.
Product Preparation:
Purified by HPLC.
Storage and Handling:
Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
