The TMEM8B Polyclonal Antibody (PAC018753) is a valuable tool for researchers studying TMEM8B, a transmembrane protein with implications in various cellular processes. This antibody, derived from rabbits, exhibits strong reactivity with human samples and is verified for use in Western blot applications. By binding to the TMEM8B protein, this antibody enables accurate detection and analysis in a range of cell types, making it ideal for investigations in molecular biology and cell signaling pathways.TMEM8B is known for its involvement in intracellular transport and membrane dynamics, suggesting a potential role in cellular trafficking and organelle function.
Its function in these processes makes it a compelling target for research in areas such as cell biology, membrane biogenesis, and protein trafficking mechanisms. By understanding the function of TMEM8B, researchers can gain insights into how cells maintain homeostasis and respond to environmental stimuli, providing opportunities for developing novel therapies and interventions in various disease contexts.
Antibody Name:
TMEM8B Antibody (PACO18753)
Antibody SKU:
PACO18753
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:1000-1:5000, IHC:1:25-1:100
Species Reactivity:
Human, Mouse
Immunogen:
Synthetic peptide of human TMEM8B
Form:
Liquid
Storage Buffer:
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method:
Antigen affinity purification
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
The image on the left is immunohistochemistry of paraffin-embedded Human gastric cancer tissue using PACO18753(TMEM8B Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: x200).
The image on the left is immunohistochemistry of paraffin-embedded Human colon cancer tissue using PACO18753(TMEM8B Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
May function as a regulator of the EGFR pathway. Probable tumor suppressor which may function in cell growth, proliferation and adhesion.
Synonyms:
Transmembrane protein 8B
UniProt Protein Function:
TMEM8B: May function as a regulator of the EGFR pathway. Probable tumor suppressor which may function in cell growth, proliferation and adhesion. Belongs to the TMEM8 family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 9p13.3Cellular Component: cell surface; mitochondrion; endoplasmic reticulum; integral to membrane; plasma membrane; nucleusMolecular Function: protein bindingBiological Process: cell-matrix adhesion; regulation of growth; regulation of mitotic cell cycle
transmembrane protein 8B; Protein NGX6; nasopharyngeal carcinoma expressed 6; nasopharyngeal carcinoma related protein; nasopharyngeal carcinoma-associated gene 6 protein; protein NAG-5
UniProt Protein Name:
Transmembrane protein 8B
UniProt Synonym Protein Names:
Nasopharyngeal carcinoma-associated gene 6 protein; Protein NAG-5; Protein NGX6
