Torvutatug Antibody is a research-grade biosimilar monoclonal antibody targeting FOLR1. It is a human IgG1, Kappa antibody. Reactivity: Human. Supplied as a liquid. Applications: ELISA, flow cytometry, functional assays and in vivo research. Endotoxin: < 10 EU/mg. Purity: >95% as determined by SDS-PAGE. For research use only.
Folate receptor alpha (FOLR1) is a ~29 kDa protein. Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. Required for normal embryonic development and normal cell proliferation. FOLR1 is the therapeutic target of mirvetuximab soravtansine (Elahere).
Product Name:
Torvutatug Antibody
SKU:
GXBS02533
Size:
100 µg, 1 mg
Antibody Type:
Monoclonal Antibody
Target:
FOLR1
Isotype:
IgG1, Kappa
Host Species:
Human
Reactivity:
Human
Applications:
ELISA, FACS, Functional assay, Research in vivo
Synonyms:
2975630-15-8
Purity:
>95% as determined by SDS-PAGE.
Endotoxin Level:
< 10 EU/mg
State of Matter:
Liquid
Regulatory Status:
For research use only. Not suitable for clinical or therapeutic use.
Storage and Handling:
Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
