UniProt Protein Function: | TP53INP2: Dual regulator of transcription and autophagy. Positively regulates autophagy and is required for autophagosome formation and processing. May act as a scaffold protein that recruits MAP1LC3A, GABARAP and GABARAPL2 and brings them to the autophagosome membrane by interacting with VMP1 where, in cooperation with the BECN1-PI3-kinase class III complex, they trigger autophagosome development. Acts as a transcriptional activator of THRA.Cellular Component: cytoplasm; autophagic vacuole; cytoplasmic vesicle; cytosol; nucleusBiological Process: osteoblast differentiation; transcription, DNA-dependent; regulation of transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; autophagy; positive regulation of autophagy; autophagic vacuole formation |
UniProt Protein Details: | |
NCBI Summary: | |
UniProt Code: | Q8CFU8 |
NCBI GenInfo Identifier: | 30017443 |
NCBI Gene ID: | 68728 |
NCBI Accession: | NP_835212.1 |
UniProt Secondary Accession: | Q8CFU8,Q3TDL6, Q711P5, Q8CHM4 |
UniProt Related Accession: | Q8CFU8 |
Molecular Weight: | 24,288 Da |
NCBI Full Name: | tumor protein p53-inducible nuclear protein 2 |
NCBI Synonym Full Names: | transformation related protein 53 inducible nuclear protein 2 |
NCBI Official Symbol: | Trp53inp2Â Â |
NCBI Official Synonym Symbols: | Tp53inp2; 1110029F20Rik  |
NCBI Protein Information: | tumor protein p53-inducible nuclear protein 2; diabetes and obesity-regulated protein; tumor protein p53 inducible nuclear protein 2 |
UniProt Protein Name: | Tumor protein p53-inducible nuclear protein 2 |
UniProt Synonym Protein Names: | Diabetes and obesity-regulated protein |
Protein Family: | Tumor protein p53-inducible nuclear protein |
UniProt Gene Name: | Tp53inp2Â Â |
UniProt Entry Name: | T53I2_MOUSE |