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TRIM21 Rabbit Polyclonal Antibody (CAB1957)

SKU:
CAB1957
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Cell Cycle
  • Cell Cycle Antibodies 1 Anti-TRIM21 Antibody CAB1957
  • Cell Cycle Antibodies 1 Anti-TRIM21 Antibody CAB1957
  • Cell Cycle Antibodies 1 Anti-TRIM21 Antibody CAB1957
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:TRIM21 Rabbit Polyclonal Antibody
SKU:CAB1957
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 86-334 of human TRIM21/SS-A (NP_003132.2).
Sequence:GTQG ERCA VHGE RLHL FCEK DGKA LCWV CAQS RKHR DHAM VPLE EAAQ EYQE KLQV ALGE LRRK QELA EKLE VEIA IKRA DWKK TVET QKSR IHAE FVQQ KNFL VEEE QRQL QELE KDER EQLR ILGE KEAK LAQQ SQAL QELI SELD RRCH SSAL ELLQ EVII VLER SESW NLKD LDIT SPEL RSVC HVPG LKKM LRTC AVHI TLDP DTAN PWLI LSED RRQV RLGD TQQS IPGN EERF DSYP MVLG A
Tested Applications:WB IHC-P IF/ICC IP ELISA
Recommended Dilution:WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells
Synonyms:SSA; RO52; SSA1; RNF81; Ro/SSA; TRIM21/SS-A
Positive Sample:Hep G2,293T,Rat lung,Hep G2
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Cytoplasmic vesicle, Nucleus, P-body, autophagosome.
Calculated MW:54kDa
Observed MW:50kDa/

This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined.

Purification Method:Affinity purification
Gene ID:6737
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of lysates from Rat lung using TRIM21/SS-A Rabbit pAb(CAB1957) at 1:1000 dilution.Secondary antibody:HRP Goat Anti-Rabbit IgG (H+L)(CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection:ECL Basic Kit (AbGn00020).Exposuretime:180s.

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