| UniProt Protein Function: | TSPAN1: is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. [provided by RefSeq, Jul 2008]Protein type: Motility/polarity/chemotaxis; Membrane protein, integral; Membrane protein, multi-passChromosomal Location of Human Ortholog: 1p34.1Cellular Component: cytoplasm; integral to plasma membrane; membrane; perinuclear region of cytoplasm; plasma membrane; vesicleMolecular Function: protein bindingBiological Process: cell migration; cell proliferation; cell surface receptor linked signal transduction; positive regulation of endocytosis; protein stabilization |
| UniProt Protein Details: | |
| NCBI Summary: | The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. [provided by RefSeq, Jul 2008] |
| UniProt Code: | O60635 |
| NCBI GenInfo Identifier: | 12643622 |
| NCBI Gene ID: | 10103 |
| NCBI Accession: | O60635.2 |
| UniProt Secondary Accession: | O60635,O60745, Q5VST0, D3DQ14 |
| UniProt Related Accession: | O60635 |
| Molecular Weight: | 26,301 Da |
| NCBI Full Name: | Tetraspanin-1 |
| NCBI Synonym Full Names: | tetraspanin 1 |
| NCBI Official Symbol: | TSPAN1Â Â |
| NCBI Official Synonym Symbols: | NET1; TM4C; TM4SFÂ Â |
| NCBI Protein Information: | tetraspanin-1 |
| UniProt Protein Name: | Tetraspanin-1 |
| UniProt Synonym Protein Names: | Tetraspan NET-1; Tetraspanin TM4-C |
| Protein Family: | |
| UniProt Gene Name: | TSPAN1Â Â |
| UniProt Entry Name: | TSN1_HUMAN |
