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Anti-TXNL1 Antibody (CAB6322)

SKU:
CAB6322
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Biology
  • Cell Biology Antibodies 10 Anti-TXNL1 Antibody CAB6322
  • Cell Biology Antibodies 10 Anti-TXNL1 Antibody CAB6322
  • Cell Biology Antibodies 10 Anti-TXNL1 Antibody CAB6322
  • Cell Biology Antibodies 10 Anti-TXNL1 Antibody CAB6322
  • Cell Biology Antibodies 10 Anti-TXNL1 Antibody CAB6322
€139 - €419
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Description

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Antibody Name:Anti-TXNL1 Antibody
Antibody SKU:CAB6322
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-289 of human TXNL1 (NP_004777.1).
Application:WB IHC IF
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:SKOV3, Mouse heart
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-289 of human TXNL1 (NP_004777.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MVGV KPVG SDPD FQPE LSGA GSRL AVVK FTMR GCGP CLRI APAF SSMS NKYP QAVF LEVD VHQC QGTA ATNN ISAT PTFL FFRN KVRI DQYQ GADA VGLE EKIK QHLE NDPG SNED TDIP KGYM DLMP FINK AGCE CLNE SDEH GFDN CLRK DTTF LESD CDEQ LLIT VAFN QPVK LYSM KFQG PDNG QGPK YVKI FINL PRSM DFEE AERS EPTQ ALEL TEDD IKED GIVP LRYV KFQN VNSV TIFV QSNQ GEEE TTRI SYFT FIGT PVQA TNMN DFKR VVGK KGES H
Gene ID:9352
Uniprot:O43396
Cellular Location:Cytoplasm, Nucleus
Calculated MW:32kDa
Observed MW:32kDa
Synonyms:TXNL1, HEL-S-114, TRP32, TXL-1, TXNL, Txl
Background:
UniProt Protein Function:TXNL1: a thiol reductase and novel subunit of the proteasome 19S particle. Interconverts reduced sulfide groups and oxidized disulfide bonds in a substrate.
UniProt Protein Details:

Protein type:Oxidoreductase

Chromosomal Location of Human Ortholog: 18q21.31

Cellular Component: cytoplasm; mitochondrion; nucleus; proteasome complex

Molecular Function:disulfide oxidoreductase activity; oxidoreductase activity, acting on sulfur group of donors, disulfide as acceptor; protein disulfide oxidoreductase activity

Biological Process: cell redox homeostasis; glycerol ether metabolic process; protein folding; sulfate assimilation

UniProt Code:O43396
NCBI GenInfo Identifier:18202039
NCBI Gene ID:9352
NCBI Accession:O43396.3
UniProt Related Accession:O43396
Molecular Weight:32,251 Da
NCBI Full Name:Thioredoxin-like protein 1
NCBI Synonym Full Names:thioredoxin like 1
NCBI Official Symbol:TXNL1  
NCBI Official Synonym Symbols:Txl; TXNL; TRP32; TXL-1; HEL-S-114  
NCBI Protein Information:thioredoxin-like protein 1
UniProt Protein Name:Thioredoxin-like protein 1
UniProt Synonym Protein Names:32 kDa thioredoxin-related protein
Protein Family:Thioredoxin
UniProt Gene Name:TXNL1  
UniProt Entry Name:TXNL1_HUMAN
Anti-TXNL1 Antibody (CAB6322)Western blot analysis of extracts of various cell lines, using TXNL1 antibody (CAB6322) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 90s.
Anti-TXNL1 Antibody (CAB6322)Immunohistochemistry of paraffin-embedded human liver damage using TXNL1 antibody (CAB6322) at dilution of 1:100 (40x lens).
Anti-TXNL1 Antibody (CAB6322)Immunohistochemistry of paraffin-embedded rat testis using TXNL1 antibody (CAB6322) at dilution of 1:100 (40x lens).
Anti-TXNL1 Antibody (CAB6322)Immunohistochemistry of paraffin-embedded rat brain using TXNL1 antibody (CAB6322) at dilution of 1:100 (40x lens).
Anti-TXNL1 Antibody (CAB6322)Immunofluorescence analysis of U2OS cells using TXNL1 antibody (CAB6322). Blue: DAPI for nuclear staining.

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