Urelumab Antibody is a research-grade biosimilar monoclonal antibody targeting CD137. It is a human IgG4-kappa antibody. Reactivity: Human. Supplied as a liquid in 0.94 mM Citricacid, 16.7mM Trisodiumcitratedihydrate, 6.2% sucrose, pH 6.5, 0.01% Tween80. Applications: ELISA, flow cytometry, functional assays and in vivo research. Endotoxin: < 10 EU/mg. Purity: >95% purity as determined by SDS-PAGE. For research use only.
Tumor necrosis factor receptor superfamily member 9 (CD137/4-1BB) is a ~27 kDa protein. Receptor for TNFSF9/4-1BBL. Conveys a signal that enhances CD8(+) T-cell survival, cytotoxicity, and mitochondrial activity, thereby promoting immunity against viruses and tumors (Probable).
