Description
Urelumab ELISA Kit
The Urelumab ELISA Kit (SKU: GXEL00201) enables sensitive, reproducible quantitative detection of Urelumab in Plasma, Serum using a quantitative ELISA format. The assay delivers a detection range of 31.25 - 2, 000 ng/mL and a sensitivity of 18.73 ng/mL and is read colorimetrically at 450 nm, making it well suited to quantitative research workflows.
Urelumab is a fully humanized agonistic monoclonal antibody targeting the CD137 receptor with potential immunostimulatory and antineoplastic activities. Urelumab specifically binds to and activates CD137-expressing immune cells, stimulating an immune response, in particular a cytotoxic T cell response, against tumor cells. Urelumab has been used in trials studying the treatment of Leukemia, Multiple Myeloma, Malignant Tumors, and Cancer-Solid Tumors and B-Cell Non-Hodgkin's Lymphoma. The antibody product was developed using Medarex's UltiMAb(R) technology and was the first UltiMAb-derived antibody in clinical development by Bristol-Myers Squibb under the December 2003 agreement with Medarex. In December 2008, enrolment was stopped for all urelumab studies following the occurrence of two hepatotoxicity-related deaths. Several years later, the clinical study on Urelumab was restarted. At present, the approval of the monoclonal antibody has not been disclosed in the relevant drug approval agency.
Supplied with pre-coated microplates and all core reagents, the Urelumab ELISA Kit gives you a validated, ready-to-use solution for Urelumab research. Get accurate and reliable results with the Urelumab ELISA Kit from Assay Genie.
| Product Name: | Urelumab ELISA Kit |
| SKU: | GXEL00201 |
| Accession: | Q07011 |
| Alternative Names: | BMS-663513, 934823-49-1 |
| Assay Type: | Quantitative |
| Detection Method: | Colorimetric |
| Sensitivity: | 18.73 ng/mL |
| Range: | 31.25 - 2, 000 ng/mL |
| Sample Type: | Plasma, Serum |
| Storage: | 2-8°C. See Storage & Stability for details. |
| Note: | For Research Use Only. Not for diagnostic procedures. |
| Parameter | Specification |
|---|---|
| Assay Type | Quantitative |
| Detection Method | Colorimetric |
| Sensitivity | 18.73 ng/mL |
| Detection Range | 31.25 - 2, 000 ng/mL |
| Recovery | 80-120% |
| Sample Types | Plasma, Serum |
When the kit was stored at the recommended temperature for 6 months, the signal intensity decreased by less than 20%. For unopened kits, if you want to prolong the storage time, please store the Standard, Detection A, Detection B and Microplate at - 20°C, the rest reagents should be store at 4°C.
Store the kit at 2-8°C on receipt. Avoid repeated freeze-thaw cycles.
