| UniProt Protein Function: | VIPR2: This is a receptor for VIP as well as PACAP-38 and -27, the activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Can be coupled to phospholipase C. Belongs to the G-protein coupled receptor 2 family. |
| UniProt Protein Details: | Protein type:Receptor, GPCR; Membrane protein, integral; Membrane protein, multi-pass; GPCR, family 2 Chromosomal Location of Human Ortholog: 7q36.3 Cellular Component: integral to plasma membrane; plasma membrane Molecular Function:G-protein coupled receptor activity Biological Process: cell-cell signaling; signal transduction |
| NCBI Summary: | This gene encodes a receptor for vasoactive intestinal peptide, a small neuropeptide. Vasoactive intestinal peptide is involved in smooth muscle relaxation, exocrine and endocrine secretion, and water and ion flux in lung and intestinal epithelia. Its actions are effected through integral membrane receptors associated with a guanine nucleotide binding protein which activates adenylate cyclase. [provided by RefSeq, Aug 2011] |
| UniProt Code: | P41587 |
| NCBI GenInfo Identifier: | 2506490 |
| NCBI Gene ID: | 7434 |
| NCBI Accession: | P41587.2 |
| UniProt Secondary Accession: | P41587,Q13053, Q15870, Q53Y09, Q6ZN22, Q9UCW0, |
| UniProt Related Accession: | P41587 |
| Molecular Weight: | 46,756 Da |
| NCBI Full Name: | Vasoactive intestinal polypeptide receptor 2 |
| NCBI Synonym Full Names: | vasoactive intestinal peptide receptor 2 |
| NCBI Official Symbol: | VIPR2Â Â |
| NCBI Official Synonym Symbols: | VPAC2; VPAC2R; VIP-R-2; VPCAP2R; PACAP-R3; DUP7q36.3; PACAP-R-3; C16DUPq36.3Â Â |
| NCBI Protein Information: | vasoactive intestinal polypeptide receptor 2 |
| UniProt Protein Name: | Vasoactive intestinal polypeptide receptor 2 |
| UniProt Synonym Protein Names: | Helodermin-preferring VIP receptor; Pituitary adenylate cyclase-activating polypeptide type III receptor; PACAP type III receptor; PACAP-R-3; PACAP-R3; VPAC2 |
| Protein Family: | Vasoactive intestinal polypeptide receptor |
| UniProt Gene Name: | VIPR2Â Â |
| UniProt Entry Name: | VIPR2_HUMAN |
