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VIR-2482 Antibody - Bioactivity-binding
Key Features

VIR-2482 Antibody (GXBS00508)

SKU GXBS00508
Product Type Research Grade Biosimilar
Antibody Type Monoclonal
Host Species Human
Reactivity Influenza A virus
Applications ELISA, FCM, Functional assay, Research in vivo
Clone ID VIR-2482
Isotype IgG1
€467 - €1,489

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Description

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VIR-2482 Antibody

VIR-2482 Antibody is a research-grade biosimilar monoclonal antibody targeting HA. It is a human IgG1 antibody. Reactivity: Influenza A virus. Supplied as a liquid in 0.01M PBS pH 7.4. Applications: ELISA, flow cytometry, functional assays and in vivo research. Endotoxin: < 10 EU/mg. Purity: >95% purity as determined by SDS-PAGE. For research use only.

Hemagglutinin (HA) is a ~62 kDa protein. Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization either through clathrin-dependent endocytosis or through clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virulence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane.

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