Vixarelimab Antibody is a research-grade biosimilar monoclonal antibody targeting OSMRB. It is a human IgG4-IgG1, Lambda antibody. Reactivity: Human. Supplied as a liquid in 0.01M PBS pH 7.4. Applications: ELISA, flow cytometry, functional assays and in vivo research. Endotoxin: < 10 EU/mg. Purity: >95% purity as determined by SDS-PAGE. For research use only.
Oncostatin-M-specific receptor subunit beta (OSMR/IL-31RB) is a ~110 kDa protein. Associates with IL31RA to form the IL31 receptor. Binds IL31 to activate STAT3 and possibly STAT1 and STAT5. Capable of transducing OSM-specific signaling events.