Description
VSIV Matrix Recombinant Protein (N-His)
VSIV Matrix Recombinant Protein (N-His) is a recombinant protein expressed in E. coli, spanning Ile41-Lys229, with an N-terminal His tag. Predicted molecular weight: 24.13 kDa. Purity: >90% as determined by SDS-PAGE. Supplied lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Applications: ELISA, immunogen, SDS-PAGE and Western blot. Matrix protein is a ~26 kDa protein. Forms a double layer around the helical nucleocapsid, the inner matrix layer binding to the N helix and the outer matrix layer binding to the envelope glycoprotein. For research use only.
Plays a major role in assembly and budding of virion, by recruiting cellular partners of the ESCRT complexes that play a key role in releasing the budding particle from the host membrane (Probable). Condensates the ribonucleocapsid core during virus assembly. Inhibits the host mRNA nuclear export thereby inducing the shut off of cellular transcription and preventing the interferon signaling and the establishment of antiviral state in infected cells. This shutoff presumably inhibits interferon signaling and thus establishment of antiviral state in virus infected cells.
| Product Name: | VSIV Matrix Recombinant Protein (N-His) |
| SKU: | GXRP10214 |
| Size: | 50 µg, 100 µg, 1 mg |
| Species: | VSIV |
| Synonyms: | matrix (M) protein, matrix (M) protein |
| Tag: | N-His |
| Expression Host: | E. coli |
| Protein Length: | Ile41-Lys229 |
| Calculated MW: | 24.13 kDa |
| UniProt: | P03519 |
| Applications: | ELISA, Immunogen, SDS-PAGE, WB |
| Purity: | >90% as determined by SDS-PAGE. |
| Form: | Lyophilized |
| Formulation: | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Reconstitution: | Reconstitute in sterile water for a stock solution. Adjust the volume of sterile water so that, after reconstitution, the final stock concentration matches the value indicated on the product label or datasheet. |
| Storage: | Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Shipping: | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Note: | For research use only |
