The XPO7 Polyclonal Antibody (CAB16108) is a powerful tool for research involving the XPO7 protein, a key player in nucleocytoplasmic transport processes essential for cell function. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for Western blot applications. By binding specifically to the XPO7 protein, researchers can effectively detect and analyze its expression in various cell types, making it an invaluable resource for studies in molecular biology and cell biology.XPO7, also known as Exportin-7, is a critical regulator of nucleocytoplasmic transport, facilitating the movement of proteins and RNAs between the nucleus and cytoplasm.
Dysregulation of this process can lead to cellular dysfunction and has been implicated in various diseases, including cancer and neurodegenerative disorders. By investigating the function of XPO7, researchers can gain insights into the mechanisms underlying these conditions and potentially identify new therapeutic targets for drug development.Overall, the XPO7 Polyclonal Antibody (CAB16108) offers researchers a reliable tool for studying the role of XPO7 in cellular processes and disease pathology. Its specificity and sensitivity make it an ideal choice for investigations aiming to elucidate the function of this important protein and its implications for human health.
Product Name:
XPO7 Rabbit Polyclonal Antibody
SKU:
CAB16108
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1000 to the C-terminus of human XPO7 (NP_055839.3).
The transport of protein and large RNAs through the nuclear pore complexes (NPC) is an energy-dependent and regulated process. The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex; see MIM 600685 and MIM 602738. The small GTPase RAN (MIM 601179) plays a key role in NLS-dependent protein import. RAN-binding protein-16 is a member of the importin-beta superfamily of nuclear transport receptors.
Purification Method:
Affinity purification
Gene ID:
23039
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using XPO7 Rabbit pAb (CAB16108) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
