Zaltenibart Antibody is a research-grade biosimilar monoclonal antibody targeting Mannose-binding lectin-associated serine protease 1. It is a chimeric IgG4-kappa antibody. Reactivity: Human. Supplied as a liquid in 0.01M PBS pH 7.4. Applications: ELISA, flow cytometry, functional assays and in vivo research. Endotoxin: < 10 EU/mg. Purity: >95% purity as determined by SDS-PAGE. For research use only.
Mannan-binding lectin serine protease 1 (MASP1) is a ~79 kDa protein. Precursor of a serum protease that activates the complement pathway of the complement system, a cascade of proteins that leads to phagocytosis and breakdown of pathogens and signaling that strengthens the adaptive immune system.