ZFAND6 Antibody (PACO52446)
- SKU:
- PACO52446
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- IHC
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
| Antibody Name: | ZFAND6 Antibody (PACO52446) |
| Antibody SKU: | PACO52446 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, IHC, IF |
| Recommended Dilutions: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human AN1-type zinc finger protein 6 protein (1-208AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Immunohistochemistry of paraffin-embedded human liver tissue using PACO52446 at dilution of 1:100. |
 | Immunofluorescent analysis of A549 cells using PACO52446 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
| Background: | Involved in regulation of TNF-α induced NF-kappa-B activation and apoptosis. Involved in modulation of 'Lys-48'-linked polyubiquitination status of TRAF2 and decreases association of TRAF2 with RIPK1. Required for PTS1 target sequence-dependent protein import into peroxisomes and PEX5 stability; may cooperate with PEX6. In vitro involved in PEX5 export from the cytosol to peroxisomes (By similarity). |
| Synonyms: | AN1-type zinc finger protein 6 (Associated with PRK1 protein) (Zinc finger A20 domain-containing protein 3), ZFAND6, AWP1 ZA20D3 |
| UniProt Protein Function: | Za20d3: Involved in regulation of TNF-alpha induced NF-kappa-B activation and apoptosis. Involved in modulation of 'Lys-48'- linked polyubiquitination status of TRAF2 and decreases association of TRAF2 with RIPK1. Required for PTS1 target sequence-dependent protein import into peroxisomes and PEX5 stability; may cooperate with PEX6. In vitro involved in PEX5 export from the cytosol to peroxisomes. 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Unknown function Chromosomal Location of Human Ortholog: 15q25.1 Cellular Component: cytoplasm Molecular Function:protein binding; DNA binding; zinc ion binding; polyubiquitin binding Biological Process: apoptosis; protein targeting to peroxisome; regulation of I-kappaB kinase/NF-kappaB cascade; negative regulation of apoptosis |
| UniProt Code: | Q6FIF0 |
| NCBI GenInfo Identifier: | 339276069 |
| NCBI Gene ID: | 54469 |
| NCBI Accession: | NP_001229844.1 |
| UniProt Secondary Accession: | Q6FIF0,O95792, Q9BQF7, Q9GZY3, D3DW92, D3DW94, |
| UniProt Related Accession: | Q6FIF0 |
| Molecular Weight: | 21,396 Da |
| NCBI Full Name: | AN1-type zinc finger protein 6 isoform a |
| NCBI Synonym Full Names: | zinc finger, AN1-type domain 6 |
| NCBI Official Symbol: | ZFAND6Â Â |
| NCBI Official Synonym Symbols: | AWP1; ZA20D3; ZFAND5BÂ Â |
| NCBI Protein Information: | AN1-type zinc finger protein 6; protein associated with PRK1; zinc finger, A20 domain containing 3 |
| UniProt Protein Name: | AN1-type zinc finger protein 6 |
| UniProt Synonym Protein Names: | Associated with PRK1 protein; Zinc finger A20 domain-containing protein 3 |
| Protein Family: | AN1-type zinc finger protein |
| UniProt Gene Name: | ZFAND6Â Â |
| UniProt Entry Name: | ZFAN6_HUMAN |
| ELISA Kits |
| Human ZFAND6 (AN1-type zinc finger 6) ELISA Kit |
| Human AN1-type zinc finger protein 6 (ZFAND6) ELISA Kit |
| Secondary Antibody |
| Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
| Recommended Products |
| Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011) |
| Anti-HRP-conjugated Beta Actin Antibody (CABC028) |