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AADAT Rabbit Polyclonal Antibody (CAB13090)

SKU:
CAB13090
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction
  • Signal Transduction Antibodies 1 Anti-AADAT Antibody CAB13090
  • Signal Transduction Antibodies 1 Anti-AADAT Antibody CAB13090
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:AADAT Rabbit Polyclonal Antibody
SKU:CAB13090
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 34-429 of human AADAT (NP_001273611.1).
Sequence:PKSM ISLA GGLP NPNM FPFK TAVI TVEN GKTI QFGE EMMK RALQ YSPS AGIP ELLS WLKQ LQIK LHNP PTIH YPPS QGQM DLCV TSGS QQGL CKVF EMII NPGD NVLL DEPA YSGT LQSL HPLG CNII NVAS DESG IVPD SLRD ILSR WKPE DAKN PQKN TPKF LYTV PNGN NPTG NSLT SERK KEIY ELAR KYDF LIIE DDPY YFLQ FNKF RVPT FLSM DVDG RVIR ADSF SKII SSGL RIGF LTGP KPLI ERVI LHIQ VSTL HPST FNQL MISQ LLHE WGEE GFMA HVDR VIDF YSNQ KDAI LAAA DKWL TGLA EWHV PAAG MFLW IKVK GIND VKEL IEEK AVKM GVLM LPGN AFYV DSSA PSPY LRAS FSSA SPEQ MDVA FQVL AQLI KESL
Tested Applications:WB IHC-P IF/ICC ELISA
Recommended Dilution:WB,1:2000 - 1:4000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200
Synonyms:KAT2; KATII; KYAT2; AADAT
Positive Sample:Mouse liver,Rat kidney
Conjugate:Unconjugated
Cellular Localization:Mitochondrion.
Calculated MW:47kDa
Observed MW:46kDa

This gene encodes a protein that is highly similar to mouse and rat kynurenine aminotransferase II. The rat protein is a homodimer with two transaminase activities. One activity is the transamination of alpha-aminoadipic acid, a final step in the saccaropine pathway which is the major pathway for L-lysine catabolism. The other activity involves the transamination of kynurenine to produce kynurenine acid, the precursor of kynurenic acid which has neuroprotective properties. Several transcript variants encoding two different isoforms have been found for this gene.

Purification Method:Affinity purification
Gene ID:51166
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates, using AADAT Rabbit pAb (CAB13090) at 1:4000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.

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