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ABCA2 Rabbit Polyclonal Antibody (CAB16735)

SKU:
CAB16735
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Signal Transduction
  • Signal Transduction Antibodies 2 Anti-ABCA2 Antibody CAB16735
  • Signal Transduction Antibodies 2 Anti-ABCA2 Antibody CAB16735
  • Signal Transduction Antibodies 2 Anti-ABCA2 Antibody CAB16735
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:ABCA2 Rabbit Polyclonal Antibody
SKU:CAB16735
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 140-350 of human ABCA2 (NP_001597.2).
Sequence:SHLD RSTV SSFS LDSV ARNP QELW RFLT QNLS LPNS TAQA LLAA RVDP PEVY HLLF GPSS ALDS QSGL HKGQ EPWS RLGG NPLF RMEE LLLA PALL EQLT CTPG SGEL GRIL TVPE SQKG ALQG YRDA VCSG QAAA RARR FSGL SAEL RNQL DVAK VSQQ LGLD APNG SDSS PQAP PPRR LQAL LGDL LDAQ KVLQ DVDV LSAL ALLL PQG
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200
Synonyms:ABC2; IDPOGSA; ABCA2
Positive Sample:HeLa,Rat brain
Conjugate:Unconjugated
Cellular Localization:Endosome membrane, Lysosome membrane, Multi-pass membrane protein.
Calculated MW:270kDa
Observed MW:270kDa

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is highly expressed in brain tissue and may play a role in macrophage lipid metabolism and neural development. Two transcript variants encoding different isoforms have been found for this gene.

Purification Method:Affinity purification
Gene ID:20
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using ABCA2 Rabbit pAb (CAB16735) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 3min.

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