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ABCE1 Rabbit Polyclonal Antibody (CAB8146)

SKU:
CAB8146
Product Type:
Antibody
Applications:
WB
IF
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Immunology
  • Immunology Antibodies 3 Anti-ABCE1 Antibody CAB8146
  • Immunology Antibodies 3 Anti-ABCE1 Antibody CAB8146
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:ABCE1 Rabbit Polyclonal Antibody
SKU:CAB8146
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 320-599 of human ABCE1 (NP_002931.2).
Sequence:ENLR FRDA SLVF KVAE TANE EEVK KMCM YKYP GMKK KMGE FELA IVAG EFTD SEIM VMLG ENGT GKTT FIRM LAGR LKPD EGGE VPVL NVSY KPQK ISPK STGS VRQL LHEK IRDA YTHP QFVT DVMK PLQI ENII DQEV QTLS GGEL QRVA LALC LGKP ADVY LIDE PSAY LDSE QRLM AARV VKRF ILHA KKTA FVVE HDFI MATY LADR VIVF DGVP SKNT VANS PQTL LAGM NKFL SQLE ITFR RDPN NYRP RINK LNSI KDVE QKKS GNYF FLDD
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:2000
Synonyms:RLI; OABP; RLI1; ABC38; RNS4I; RNASEL1; RNASELI; ABCE1
Positive Sample:MCF7,Jurkat,293T,HeLa,Mouse liver
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Mitochondrion.
Calculated MW:67kDa
Observed MW:67kDa

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor, this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system, the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene.

Purification Method:Affinity purification
Gene ID:6059
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using ABCE1 antibody (CAB8146) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.

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