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ACTL6B Rabbit Polyclonal Antibody (CAB7108)

SKU:
CAB7108
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Neuroscience
  • Neuroscience Anti-ACTL6B Antibody CAB7108
  • Neuroscience Anti-ACTL6B Antibody CAB7108
  • Neuroscience Anti-ACTL6B Antibody CAB7108
  • Neuroscience Anti-ACTL6B Antibody CAB7108
  • Neuroscience Anti-ACTL6B Antibody CAB7108
€139 - €419
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:ACTL6B Rabbit Polyclonal Antibody
SKU:CAB7108
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-280 of human ACTL6B (NP_057272.1).
Sequence:MSGG VYGG DEVG ALVF DIGS FSVR AGYA GEDC PKAD FPTT VGLL AAEE GGGL ELEG DKEK KGKI FHID TNAL HVPR DGAE VMSP LKNG MIED WECF RAIL DHTY SKHV KSEP NLHP VLMS EAPW NTRA KREK LTEL MFEQ YNIP AFFL CKTA VLTA FANG RSTG LVLD SGAT HTTA IPVH DGYV LQQG IVKS PLAG DFIS MQCR ELFQ EMAI DIIP PYMI AAKE PVRE GAPP NWKK KEKL PQVS KSWH NYMC NEVI QDFQ ASVL QVSD SPYD EQVA AQMP
Tested Applications:WB IHC-P IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:100
Synonyms:ACTL6; DEE76; BAF53B; EIEE76; IDDSSAD; SMARCN2; arpNalpha; ACTL6B
Positive Sample:HL-60,22Rv1,BT-474,HeLa,HepG2,Mouse brain,Mouse skeletal muscle
Conjugate:Unconjugated
Cellular Localization:Nucleus.
Calculated MW:47kDa
Observed MW:47-55kDa

The protein encoded by this gene is a member of a family of actin-related proteins (ARPs) which share significant amino acid sequence identity to conventional actins. Both actins and ARPs have an actin fold, which is an ATP-binding cleft, as a common feature. The ARPs are involved in diverse cellular processes, including vesicular transport, spindle orientation, nuclear migration and chromatin remodeling. This gene encodes a subunit of the BAF (BRG1/brm-associated factor) complex in mammals, which is functionally related to SWI/SNF complex in S. cerevisiae and Drosophila; the latter is thought to facilitate transcriptional activation of specific genes by antagonizing chromatin-mediated transcriptional repression. This subunit may be involved in the regulation of genes by structural modulation of their chromatin, specifically in the brain. Alternative splicing results in multiple transcript variants.

Purification Method:Affinity purification
Gene ID:51412
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using ACTL6B Rabbit pAb (CAB7108) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 40s.

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