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ACVR1C Rabbit Polyclonal Antibody (CAB0678)

SKU:
CAB0678
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cell Death
  • Cell Death Antibodies 1 Anti-ACVR1C Antibody CAB0678
  • Cell Death Antibodies 1 Anti-ACVR1C Antibody CAB0678
  • Cell Death Antibodies 1 Anti-ACVR1C Antibody CAB0678
  • Cell Death Antibodies 1 Anti-ACVR1C Antibody CAB0678
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:ACVR1C Rabbit Polyclonal Antibody
SKU:CAB0678
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 22-113 of human ACVR1C (NP_660302.2).
Sequence:LSPG LKCV CLLC DSSN FTCQ TEGA CWAS VMLT NGKE QVIK SCVS LPEL NAQV FCHS SNNV TKTE CCFT DFCN NITL HLPT ASPN APKL GPME
Tested Applications:WB IHC-P ELISA
Recommended Dilution:WB,1:500 - 1:1000 IHC-P,1:100 - 1:200
Synonyms:ALK7; ACVRLK7; ACVR1C
Positive Sample:HT-29,BxPC-3,Mouse brain,Rat brain
Conjugate:Unconjugated
Cellular Localization:Membrane, Single-pass type I membrane protein.
Calculated MW:55kDa
Observed MW:55kDa

ACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al., 2001 [PubMed 12063393]).

Purification Method:Affinity purification
Gene ID:130399
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using ACVR1C Rabbit pAb (CAB0678) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.

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