The ADIPOR1 Antibody (CAB16527) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high specificity for adipor1 in human samples and has been validated for use in Western blot applications.Adipor1, also known as adiponectin receptor 1, plays a crucial role in mediating the metabolic effects of adiponectin, a hormone that regulates glucose levels and fatty acid breakdown. Dysregulation of adipor1 signaling has been linked to metabolic disorders such as obesity, insulin resistance, and type 2 diabetes, making it a promising target for therapeutic intervention.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse, Rat samples.
Product Name:
ADIPOR1 Antibody
SKU:
CAB16527
Size:
20μL, 100μL
Reactivity:
Mouse, Rat
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
CGI45, PAQR1, ACDCR1, CGI-45, TESBP1A, ADIPOR1
Positive Sample:
Mouse skeletal muscle, Rat skeletal muscle
Cellular Localization:
Cell Membrane, Multi-Pass Membrane Protein.
Calculated MW:
43kDa
Observed MW:
45kDa
This gene encodes a protein which acts as a receptor for adiponectin, a hormone secreted by adipocytes which regulates fatty acid catabolism and glucose levels. Binding of adiponectin to the encoded protein results in activation of an AMP-activated kinase signaling pathway which affects levels of fatty acid oxidation and insulin sensitivity. A pseudogene of this gene is located on chromosome 14. Multiple alternatively spliced transcript variants have been found for this gene.
Purification Method
Affinity purification
Gene ID
51094
RRID
AB_2768262
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ADIPOR1 Rabbit pAb (CAB16527) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates / proteins: 25 μg per lane. Blocking buffer: 3 % nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
