Aflibercept (Research-Grade) is a research-grade biosimilar monoclonal antibody targeting Vascular endothelial growth factor A. It is a human IgG1-Fc antibody. Reactivity: Human. Supplied as a liquid in 0.01M PBS pH 7.4. Applications: ELISA, functional assays and in vivo research. Endotoxin: < 10 EU/mg. Purity: >95% purity as determined by SDS-PAGE. For research use only.
Vascular endothelial growth factor A, long form (VEGFA) is a ~43 kDa protein. Participates in the induction of key genes involved in the response to hypoxia and in the induction of angiogenesis such as HIF1A. Involved in protecting cells from hypoxia-mediated cell death. VEGFA is the therapeutic target of bevacizumab (Avastin).
Product Name:
Aflibercept (Research-Grade)
SKU:
GXBS00523
Size:
100 µg, 1 mg
Antibody Type:
Monoclonal Antibody
Target:
L-VEGF
Isotype:
IgG1-Fc
Host Species:
Human
Reactivity:
Human
Applications:
ELISA, Functional assay, Research in vivo
Synonyms:
CAS: 862111-32-8
Recommended Dilutions:
ELISA: 1:2000-1:20000
Purity:
>95% as determined by SDS-PAGE.
Endotoxin Level:
< 10 EU/mg
Formulation:
0.01M PBS pH 7.4.
State of Matter:
Liquid
Regulatory Status:
For research use only. Not suitable for clinical or therapeutic use.
Product Preparation:
Protein A/G purified from cell culture supernatant.
Storage and Handling:
Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
