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Anti-AHCYL1 Antibody (CAB7773)

SKU:
CAB7773
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Metabolism
  • Metabolism Antibodies 2 Anti-AHCYL1 Antibody CAB7773
  • Metabolism Antibodies 2 Anti-AHCYL1 Antibody CAB7773
  • Metabolism Antibodies 2 Anti-AHCYL1 Antibody CAB7773
€139 - €419
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Description

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Antibody Name:Anti-AHCYL1 Antibody
Antibody SKU:CAB7773
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 31-260 of human AHCYL1 (NP_006612.2).
Application:WB IHC
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:293T, U-251MG, SKOV3, Mouse brain, Rat spinal cord
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 31-260 of human AHCYL1 (NP_006612.2).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MATV TKAP KKQI QFAD DMQE FTKF PTKT GRRS LSRS ISQS STDS YSSA ASYT DSSD DEVS PREK QQTN SKGS SNFC VKNI KQAE FGRR EIEI AEQD MSAL ISLR KRAQ GEKP LAGA KIVG CTHI TAQT AVLI ETLC ALGA QCRW SACN IYST QNEV AAAL AEAG VAVF AWKG ESED DFWW CIDR CVNM DGWQ ANMI LDDG GDLT HWVY KKYP NVFK KIRG IVEE SVTG VH
Gene ID:10768
Uniprot:O43865
Cellular Location:Apical cell membrane, Cytoplasm, Endoplasmic reticulum, Microsome, cytosol
Calculated MW:53kDa/58kDa
Observed MW:59kDa
Synonyms:AHCYL1, DCAL, IRBIT, PPP1R78, PRO0233, XPVKONA
Background:The protein encoded by this gene interacts with inositol 1, 4, 5-trisphosphate receptor, type 1 and may be involved in the conversion of S-adenosyl-L-homocysteine to L-homocysteine and adenosine. Several transcript variants encoding two different isoforms have been found for this gene.
NCBI Summary:This gene encodes a member of the RGS (regulator of G protein signaling) family of proteins, which are defined by the presence of a RGS domain that confers the GTPase-activating activity of these proteins toward certain G alpha subunits. This protein also belongs to a subfamily of RGS proteins characterized by the presence of DEP and GGL domains, the latter a G beta 5-interacting domain. The RGS proteins negatively regulate G protein signaling, and may modulate neuronal, cardiovascular, lymphocytic activities, and cancer risk. Many alternatively spliced transcript variants encoding different isoforms with long or short N-terminal domains, complete or incomplete GGL domains, and distinct C-terminal domains, have been described for this gene, however, the full-length nature of some of these variants is not known.[provided by RefSeq, Mar 2011]
UniProt Code:O43865
NCBI GenInfo Identifier:109731743
NCBI Gene ID:9628
NCBI Accession:BC113572
UniProt Secondary Accession:O43865,O75576, O75577, Q7Z4K3, Q7Z4K4, Q7Z4K5, Q7Z4K6 Q8TE13, Q8TE14, Q8TE15, C9JE95, F8W7W5,
UniProt Related Accession:P49758
Molecular Weight:53,319 Da
NCBI Full Name:Homo sapiens regulator of G-protein signaling 6, mRNA
NCBI Synonym Full Names:regulator of G-protein signaling 6
NCBI Official Symbol:RGS6  
NCBI Official Synonym Symbols:GAP; S914; HA117  
NCBI Protein Information:regulator of G-protein signaling 6
UniProt Protein Name:Putative adenosylhomocysteinase 2
UniProt Synonym Protein Names:DC-expressed AHCY-like molecule; IP(3)Rs binding protein released with IP(3); IRBIT; S-adenosyl-L-homocysteine hydrolase 2; S-adenosylhomocysteine hydrolase-like protein 1
Protein Family:Regulator of G-protein signaling
UniProt Gene Name:AHCYL1  
UniProt Entry Name:SAHH2_HUMAN
Anti-AHCYL1 Antibody (CAB7773)Western blot analysis of extracts of various cell lines, using AHCYL1 antibody (CAB7773) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25ug per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Basic Kit (RM00020)._Exposure time: 90s.
Anti-AHCYL1 Antibody (CAB7773)Immunohistochemistry of paraffin-embedded human stomach using AHCYL1 antibody (CAB7773) at dilution of 1:100 (40x lens).
Anti-AHCYL1 Antibody (CAB7773)Immunohistochemistry of paraffin-embedded rat kidney using AHCYL1 antibody (CAB7773) at dilution of 1:100 (40x lens).

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