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Andecaliximab Antibody - Bioactivity-binding
Key Features

Andecaliximab Antibody (GXBS00350)

SKU GXBS00350
Product Type Research Grade Biosimilar
Antibody Type Monoclonal
Host Species Chimeric
Reactivity Human
Applications ELISA, FACS, Functional assay, Research in vivo
Isotype IgG4-kappa
$409 - $1,138

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Description

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Andecaliximab Antibody

Andecaliximab Antibody is a research-grade biosimilar monoclonal antibody targeting Matrix metalloproteinase-9. It is a chimeric IgG4-kappa antibody. Reactivity: Human. Supplied as a liquid in 0.01M PBS pH 7.4. Applications: ELISA, flow cytometry, functional assays and in vivo research. Endotoxin: < 10 EU/mg. Purity: >95% purity as determined by SDS-PAGE. For research use only.

Matrix metalloproteinase-9 (MMP9) is a ~78 kDa protein. Matrix metalloproteinase that plays an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly-|-Leu bond. Cleaves NINJ1 to generate the Secreted ninjurin-1 form. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments.

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