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ANGPT2 Rabbit Polyclonal Antibody (CAB0698)

SKU:
CAB0698
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Cardiovascular
  • Cardiovascular Antibodies Anti-ANGPT2 Antibody CAB0698
  • Cardiovascular Antibodies Anti-ANGPT2 Antibody CAB0698
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:ANGPT2 Rabbit Polyclonal Antibody
SKU:CAB0698
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 197-496 of human ANGPT2 (NP_001138.1).
Sequence:AMED KHII QLQS IKEE KDQL QVLV SKQN SIIE ELEK KIVT ATVN NSVL QKQQ HDLM ETVN NLLT MMST SNSA KDPT VAKE EQIS FRDC AEVF KSGH TTNG IYTL TFPN STEE IKAY CDME AGGG GWTI IQRR EDGS VDFQ RTWK EYKV GFGN PSGE YWLG NEFV SQLT NQQR YVLK IHLK DWEG NEAY SLYE HFYL SSEE LNYR IHLK GLTG TAGK ISSI SQPG NDFS TKDG DNDK CICK CSQM LTGG WWFD ACGP SNLN GMYY PQRQ NTNK FNGI KWYY WKGS GYSL KATT MMIR PADF
Tested Applications:WB IF/ICC ELISA
Recommended Dilution:WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200
Synonyms:ANG2; AGPT2; LMPHM10; ANGPT2
Positive Sample:A-549,HT-29,HepG2,K-562,Raji,Mouse brain,Mouse spleen,Rat kidney,Rat heart
Conjugate:Unconjugated
Cellular Localization:Secreted.
Calculated MW:57kDa
Observed MW:75kDa

This gene belongs to the angiopoietin family of growth factors. The protein encoded by this gene is an antagonist of angiopoietin 1, and both angiopoietin 1 and angiopoietin 2 are ligands for the endothelial TEK receptor tyrosine kinase. Angiopoietin 2 is upregulated in multiple inflammatory diseases and is implicated in the direct control of inflammation-related signaling pathways. The encoded protein affects angiogenesis during embryogenesis and tumorigenesis, disrupts the vascular remodeling ability of angiopoietin 1, and may induce endothelial cell apoptosis. This gene serves a prognostic biomarker for acute respiratory distress syndrome.

Purification Method:Affinity purification
Gene ID:285
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using ANGPT2 Rabbit pAb (CAB0698) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.

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