null

Anti-ANP32A Antibody (CAB5768)

SKU:
CAB5768
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Antibody Type:
Polyclonal Antibody
Research Area:
Epigenetics and Nuclear Signaling
  • Epigenetics and Nuclear Signaling Antibodies 2 Anti-ANP32A Antibody CAB5768
  • Epigenetics and Nuclear Signaling Antibodies 2 Anti-ANP32A Antibody CAB5768
  • Epigenetics and Nuclear Signaling Antibodies 2 Anti-ANP32A Antibody CAB5768
  • Epigenetics and Nuclear Signaling Antibodies 2 Anti-ANP32A Antibody CAB5768
  • Epigenetics and Nuclear Signaling Antibodies 2 Anti-ANP32A Antibody CAB5768
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Antibody Name:Anti-ANP32A Antibody
Antibody SKU:CAB5768
Antibody Size:20uL, 50uL, 100uL
Application:WB IHC IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human ANP32A (NP_006296.1).
Application:WB IHC IF
Recommended Dilution:WB 1:500 - 1:2000 IHC 1:50 - 1:200 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:293T, HepG2, HL-60, MCF7, Raji, U-251MG, Mouse brain, HT-29
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human ANP32A (NP_006296.1).
Purification Method:Affinity purification
Storage Buffer:Store at -20'C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:MEMG RRIH LELR NRTP SDVK ELVL DNSR SNEG KLEG LTDE FEEL EFLS TINV GLTS IANL PKLN KLKK LELS DNRV SGGL EVLA EKCP NLTH LNLS GNKI KDLS TIEP LKKL ENLK SLDL FNCE VTNL NDYR ENVF KLLP QLTY LDGY DRDD KEAP DSDA EGYV EGLD DE
Gene ID:8125
Uniprot:P39687
Cellular Location:Cytoplasm, Endoplasmic reticulum, Nucleus
Calculated MW:28kDa
Observed MW:28kDa
Synonyms:ANP32A, C15orf1, HPPCn, I1PP2A, LANP, MAPM, PHAP1, PHAPI, PP32
Background:
UniProt Protein Function:ANP32A: Implicated in a number of cellular processes, including proliferation, differentiation, caspase-dependent and caspase- independent apoptosis, suppression of transformation (tumor suppressor), inhibition of protein phosphatase 2A, regulation of mRNA trafficking and stability in association with ELAVL1, and inhibition of acetyltransferases as part of the INHAT (inhibitor of histone acetyltransferases) complex. Plays a role in E4F1- mediated transcriptional repression. Belongs to the ANP32 family.
UniProt Protein Details:

Protein type:Nuclear receptor co-regulator; Transcription, coactivator/corepressor

Chromosomal Location of Human Ortholog: 15q23

Cellular Component: nucleoplasm; endoplasmic reticulum; perinuclear region of cytoplasm; cytoplasm; nucleus

Molecular Function:protein binding

Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent; nucleocytoplasmic transport; gene expression

UniProt Code:P39687
NCBI GenInfo Identifier:730318
NCBI Gene ID:8125
NCBI Accession:P39687.1
UniProt Secondary Accession:P39687,Q53FK4, Q5J8L8, Q7M4N6, B2R6T4,
UniProt Related Accession:P39687
Molecular Weight:28,585 Da
NCBI Full Name:Acidic leucine-rich nuclear phosphoprotein 32 family member A
NCBI Synonym Full Names:acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
NCBI Official Symbol:ANP32A  
NCBI Official Synonym Symbols:LANP; MAPM; PP32; HPPCn; PHAP1; PHAPI; I1PP2A; C15orf1  
NCBI Protein Information:acidic leucine-rich nuclear phosphoprotein 32 family member A; mapmodulin; hepatopoietin Cn; acidic nuclear phosphoprotein pp32; leucine-rich acidic nuclear protein; putative HLA-DR-associated protein I; inhibitor-1 of protein phosphatase-2A; cerebellar leucine rich acidic nuclear protein; putative human HLA class II associated protein I; potent heat-stable protein phosphatase 2A inhibitor I1PP2A
UniProt Protein Name:Acidic leucine-rich nuclear phosphoprotein 32 family member A
UniProt Synonym Protein Names:Acidic nuclear phosphoprotein pp32; pp32; Leucine-rich acidic nuclear protein; LANP; Mapmodulin; Potent heat-stable protein phosphatase 2A inhibitor I1PP2A; Putative HLA-DR-associated protein I; PHAPI
Protein Family:Acidic leucine-rich nuclear phosphoprotein 32 family
UniProt Gene Name:ANP32A  
UniProt Entry Name:AN32A_HUMAN
Anti-ANP32A Antibody (CAB5768)Western blot analysis of extracts of various cell lines, using ANP32A antibody (CAB5768) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (RM00020). Exposure time: 30s.
Anti-ANP32A Antibody (CAB5768)Immunohistochemistry of paraffin-embedded rat kidney using ANP32A Antibody (CAB5768) at dilution of 1:100 (40x lens).
Anti-ANP32A Antibody (CAB5768)Immunohistochemistry of paraffin-embedded human breast cancer using ANP32A Antibody (CAB5768) at dilution of 1:100 (40x lens).
Anti-ANP32A Antibody (CAB5768)Immunohistochemistry of paraffin-embedded mouse brain using ANP32A Antibody (CAB5768) at dilution of 1:100 (40x lens).
Anti-ANP32A Antibody (CAB5768)Immunofluorescence analysis of A549 cells using ANP32A antibody (CAB5768). Blue: DAPI for nuclear staining.

Related Products