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Anti-CTIP2/BCL11B Antibody (CAB19804)

SKU:
CAB19804
Product type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
ATL1
Synonyms:
ATL1-alpha
Synonyms:
ATL1-beta
Synonyms:
ATL1-delta
Synonyms:
ATL1-gamma
Synonyms:
CTIP-2
Synonyms:
CTIP2
Synonyms:
IMD49
Synonyms:
RIT1
Synonyms:
ZNF856B
Synonyms:
hRIT1-alpha
€159 - €419
Frequently bought together:

Description

Product Name:CTIP2/BCL11B Rabbit mAb
Product Code:CAB19804
Size:20uL, 50uL, 100uL
Synonyms:ATL1, ATL1-alpha, ATL1-beta, ATL1-delta, ATL1-gamma, CTIP-2, CTIP2, IMD49, RIT1, ZNF856B, hRIT1-alpha
Applications:WB, IHC
Reactivity:Human, Mouse
Host Species:Rabbit
Immunogen:A synthesized peptide derived from human CTIP2/BCL11B
Applications:WB, IHC
Recommended Dilutions:WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:Human, Mouse
Positive Samples:Jurkat, Raji, SH-SY5Y
Immunogen:A synthesized peptide derived from human CTIP2/BCL11B
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:64919
Uniprot:Q9C0K0
Calculated MW:140kDa
Observed MW:120-130KDa
UniProt Protein Function:Tumor-suppressor protein involved in T-cell lymphomas. May function on the P53-signaling pathway. May be a key regulator of both differentiation and survival during thymocyte development. Repress transcription through direct, TFCOUP2-independent binding to a GC-rich response element.
NCBI Summary:This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. Although the specific function of this gene has not been determined, the encoded protein is known to be a transcriptional repressor, and is regulated by the NURD nucleosome remodeling and histone deacetylase complex. Four alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Aug 2013]
UniProt Code:Q9C0K0
NCBI GenInfo Identifier:44887723
NCBI Gene ID:64919
NCBI Accession:Q9C0K0.1
UniProt Secondary Accession:Q9C0K0,Q9H162,
UniProt Related Accession:Q9C0K0
Molecular Weight:88,476 Da
NCBI Full Name:B-cell lymphoma/leukemia 11B
NCBI Synonym Full Names:B-cell CLL/lymphoma 11B
NCBI Official Symbol:BCL11B  
NCBI Official Synonym Symbols:ATL1; RIT1; CTIP2; CTIP-2; ZNF856B; ATL1-beta; ATL1-alpha; ATL1-delta; ATL1-gamma; hRIT1-alpha  
NCBI Protein Information:B-cell lymphoma/leukemia 11B
UniProt Protein Name:B-cell lymphoma/leukemia 11B
UniProt Synonym Protein Names:B-cell CLL/lymphoma 11B; COUP-TF-interacting protein 2; Radiation-induced tumor suppressor gene 1 protein; hRit1
Protein Family:B-cell lymphoma/leukemia
UniProt Gene Name:BCL11B  
UniProt Entry Name:BC11B_HUMAN

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