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Anti-Digoxin Antibody CAB20267
Key Features

Digoxin Rabbit Monoclonal Antibody (CAB20267)

Datasheet MSDS
SKU CAB20267
Product Type Antibody
Antibody Type Monoclonal Antibody
Reactivity Species independent
Host Species Rabbit
$173 - $603

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Description

system_update_altDatasheetsystem_update_altMSDS

Digoxin Monoclonal Antibody (CAB20267)

The Digoxin Monoclonal Antibody (CAB20267) is a high-quality antibody developed for reliable detection and analysis of target proteins. The antibody, produced in rabbits, is reactive with digoxin in various samples and is validated for use in applications such as ELISA and immunohistochemistry.Digoxin is a cardiac glycoside that works by increasing the force of contraction of the heart muscle, making it an important medication for managing heart failure and certain arrhythmias.

This antibody is validated for use in ELISA, DB applications and has demonstrated reactivity against Species independent samples.

Product Name:Digoxin Monoclonal Antibody
SKU:CAB20267
Size:20μL, 100μL
Reactivity:Species independent
Clone Number:ARC50289
Conjugate:Unconjugated
Immunogen:Chemical compounds corresponding to Digoxigenin/Digoxin.
Sequence:Digo xin conj ugat ed t o KL H
Tested Applications:ELISA DB
Recommended Dilution:
DB1:500 - 1:3000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Observed MW:Refertofigures

Digoxin is a cardiac glycoside. Digoxin inhibits the sodium potassium adenosine triphosphatase (ATPase) pump, thereby increasing intracellular calcium and enhancing cardiac contractility. This agent also acts directly on the atrioventricular node to suppress conduction, thereby slowing conduction velocity. Apparently due to its effects on intracellular calcium concentrations, digoxin induces apoptosis of tumor cells via a pathway involving mitochondrial cytochrome c, caspases 8 and 3.

Purification MethodAffinity purification
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageThe Anti-Digoxigenin/Digoxin Rabbit mAb (CAB20267) are tested in Dot Blot against digoxin labelled oligonucleotide(Dig-1，Dig-2 and Dig-3) and unlabelled oligonucleotide(Dig-4) Dig-1 :5'AGCTAAC/iDigdT/ACTAGCT(Biotin)3' Dig-2 :5'(Digoxin)AGCTAACTACTAGCT(Biotin)3' Dig-3 :5'(Biotin)AGCTAACTACTAGCT(Digoxin)3' Dig-4 :5'AGCTAACTACTAGCT(Biotin)3'
Product ImageThe Anti-Digoxigenin/Digoxin Rabbit mAb (CAB20267) are tested in ELISA against digoxin labelled oligonucleotide(Dig-1，Dig-2 and Dig-3) and unlabelled oligonucleotide(Dig-4) Dig-1 :5'AGCTAAC/iDigdT/ACTAGCT(Biotin)3' Dig-2 :5'(Digoxin)AGCTAACTACTAGCT(Biotin)3' Dig-3 :5'(Biotin)AGCTAACTACTAGCT(Digoxin)3' Dig-4 :5'AGCTAACTACTAGCT(Biotin)3'
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