The Anti-DLX5 Antibody (CAB5586) is a high-quality research tool designed for studying the DLX5 protein, a transcription factor involved in embryonic development and cell differentiation. This antibody, produced in rabbits, is highly specific for detecting DLX5 in human samples and has been validated for use in Western blot and immunohistochemistry applications.DLX5 plays a key role in regulating gene expression during development, particularly in the formation of bones and teeth. Dysregulation of DLX5 has been implicated in various diseases, including craniofacial abnormalities and certain cancers.
By targeting DLX5, researchers can further investigate its functions and potential therapeutic implications in these conditions.The Anti-DLX5 Antibody is a valuable tool for researchers in the fields of developmental biology, oncology, and regenerative medicine. Its high specificity and sensitivity make it ideal for studying the expression and localization of DLX5 in different tissues and cell types, providing insights into its biological roles and potential as a therapeutic target.
Product Name:
DLX5 Rabbit Monoclonal Antibody
SKU:
CAB5586
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 150-250 of human DLX5 (P56178).
This gene encodes a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene. The encoded protein may play a role in bone development and fracture healing. Mutation in this gene, which is located in a tail-to-tail configuration with another member of the family on the long arm of chromosome 7, may be associated with split-hand/split-foot malformation.
Purification Method:
Affinity purification
Gene ID:
1749
Clone Number:
ARC1994
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using DLX5 Rabbit mAb (CAB5586) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
