Anti-eIF2A Antibody (CAB9709)
- SKU:
- CAB9709
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- CDA02
- EIF-2A
- MST089
- MSTP004
- MSTP089
- Research Area:
- Metabolism
Frequently bought together:
Description
| Product Name: | eIF2A Rabbit mAb |
| Product Code: | CAB9709 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | CDA02, EIF-2A, MST089, MSTP004, MSTP089 |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human eIF2A |
| Applications: | WB, IHC |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | BxPC-3, Mouse liver, Rat lung |
| Immunogen: | A synthesized peptide derived from human eIF2A |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 83939 |
| Uniprot: | Q9BY44 |
| Calculated MW: | 65kDa |
| Observed MW: | 60kDa |
| UniProt Protein Function: | Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40S subunits in a GTP-dependent manner. |
| NCBI Summary: | This gene encodes a eukaryotic translation initiation factor that catalyzes the formation of puromycin-sensitive 80 S preinitiation complexes and the poly(U)-directed synthesis of polyphenylalanine at low concentrations of Mg2+. This gene should not be confused with eIF2-alpha (EIF2S1, Gene ID: 1965), the alpha subunit of the eIF2 translation initiation complex. Although both of these proteins function in binding initiator tRNA to the 40 S ribosomal subunit, the encoded protein does so in a codon-dependent manner, whereas eIF2 complex requires GTP. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016] |
| UniProt Code: | Q9BY44 |
| NCBI GenInfo Identifier: | 209572747 |
| NCBI Gene ID: | 83939 |
| NCBI Accession: | Q9BY44.3 |
| UniProt Secondary Accession: | Q9BY44,Q5QTR2, Q7Z4E9, Q8NFM1, Q96EW9, Q96K81, A8MPS6 B4DF96, B4DQ14, D3DNI9, |
| UniProt Related Accession: | Q9BY44 |
| Molecular Weight: | 62 kDa |
| NCBI Full Name: | Eukaryotic translation initiation factor 2A |
| NCBI Synonym Full Names: | eukaryotic translation initiation factor 2A |
| NCBI Official Symbol: | EIF2AÂ Â |
| NCBI Official Synonym Symbols: | CDA02; EIF-2A; MST089; MSTP004; MSTP089Â Â |
| NCBI Protein Information: | eukaryotic translation initiation factor 2A |
| UniProt Protein Name: | Eukaryotic translation initiation factor 2A |
| UniProt Synonym Protein Names: | 65 kDa eukaryotic translation initiation factor 2A |
| Protein Family: | Eukaryotic translation initiation factor |
| UniProt Gene Name: | EIF2AÂ Â |
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