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Anti-EIF4A1/EIF4A2/EIF4A3 Antibody (CAB20251)

SKU:
CAB20251
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Research Area:
Immunology
€139 - €419
Frequently bought together:

Description

Product Name:EIF4A1/EIF4A2/EIF4A3 Rabbit pAb
Product Code:CAB20251
Size:50uL, 100uL
Applications:WB, IF
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:A synthetic peptide of human EIF4A1/EIF4A2/EIF4A3.
Applications:WB, IF
Recommended Dilutions:WB 1:1000 - 1:2000 IF 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:293T, HeLa, HepG2, MCF7, C2C12, Mouse brain, Rat brain
Immunogen:A synthetic peptide of human EIF4A1/EIF4A2/EIF4A3.
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:1973/1974/9775
Uniprot:P60842/Q14240/P38919
Observed MW:46KDa
UniProt Protein Function:ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.
UniProt Code:P60842
NCBI GenInfo Identifier:46397463
NCBI Gene ID:1973
NCBI Accession:P60842.1
UniProt Secondary Accession:P60842,P04765, Q5U018, Q61516, B2R6L8, D3DTP9, J3QLC4
UniProt Related Accession:P60842
Molecular Weight:39,548 Da
NCBI Full Name:Eukaryotic initiation factor 4A-I
NCBI Synonym Full Names:eukaryotic translation initiation factor 4A1
NCBI Official Symbol:EIF4A1  
NCBI Official Synonym Symbols:DDX2A; EIF4A; EIF-4A; eIF4A-I; eIF-4A-I  
NCBI Protein Information:eukaryotic initiation factor 4A-I
UniProt Protein Name:Eukaryotic initiation factor 4A-I
UniProt Synonym Protein Names:ATP-dependent RNA helicase eIF4A-1
Protein Family:Eukaryotic initiation factor
UniProt Gene Name:EIF4A1  
UniProt Entry Name:IF4A1_HUMAN

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