Anti-Human CD151 In Vivo Antibody

Product Name:	Anti-Human CD151 In Vivo Antibody - Low Endotoxin
Product Code:	IVMB0312
Size:	1 mg, 5 mg, 25 mg, 50 mg, 100 mg
Clone:	50-6
Protein:	CD151
Product Type:	Monoclonal Antibody
Synonyms:	PETA-3, Platelet-Endothelial tetra-span antigen, Tspan-24
Isotype:	IgG1 k
Reactivity:	Human
Applications:	B, CyTOF®, FC, ICC, In Vivo, WB
Formulation:	This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
Endotoxin Level:	< 1.0 EU/mg as determined by the LAL method
Purity:	≥95% monomer by analytical SEC ⋅ >95% by SDS Page
Product Preparation:	Functional grade preclinical antibodies are manufactured in an animal free facility using in vitro cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates.

Applications:	B, CyTOF®, FC, ICC, In Vivo, WB
Reactivity:	Human

Host Species:	Mouse
Specificity:	Clone 50-6 recognizes an epitope on human CD151.
Antigen Distribution:	CD151 is found on immature hematopoietic cells, megakaryocytes, platelets, keratinocytes, epithelial cells, muscle cells, Schwann cells, vascular endothelium, and activated T-cells.
Immunogen:	Human epidermoid carcinoma cell line HEp-3
Concentration:	≥ 2.0 mg/ml
Endotoxin Level:	< 1.0 EU/mg as determined by the LAL method
Formulation:	This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration.
Purity:	≥95% monomer by analytical SEC ⋅ >95% by SDS Page
Preparation:	Functional grade preclinical antibodies are manufactured in an animal free facility using in vitro cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates.
Storage and Handling:	Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.

CD151 is a 29 kD cell surface glycoprotein that is a member of the transmembrane 4 superfamily (tetraspanin family), which is characterized by cell-surface proteins consisting of four hydrophobic domains that mediate signal transduction events involved in the regulation of cell development, activation, growth and motility. CD151 is known to complex with integrins and other transmembrane 4 superfamily proteins and is involved in cell adhesion, migration, and tumor cell metastasis.

Protein:	CD151
Function:	Cell adhesion, migration
Ligand/Receptor:	CD9, CD181, integrins α3β1, α5β1 and α6β4
Shipping:	2-8°C
NCBI Gene Bank ID:	977
UniProt:	CD151