null

Anti-ICAM1 Antibody (CAB20472)

SKU:
CAB20472
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
MAL
CD54
Icam
Ly-4
Ly-47
Icam-1
MALA-2
$167 - $503
Frequently bought together:

Description

Product Name:ICAM1 Rabbit pAb
Product Code:CAB20472
Size:50uL, 100uL
Synonyms:MAL, CD54, Icam, Ly-4, Ly-47, Icam-1, MALA-2
Applications:WB, IHC
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:Recombinant protein of Mouse ICAM1.
Applications:WB, IHC
Recommended Dilutions:WB 1:500 - 1:2000 IHC 1:50 - 1:200
Reactivity:Human, Mouse, Rat
Positive Samples:Rat lung
Immunogen:Recombinant protein of Mouse ICAM1.
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:15894
Uniprot:P13597
Calculated MW:58kDa
Observed MW:85KDa
UniProt Protein Function:ICAM1: a type I membrane protein of the immunoglobulin superfamily. Is a ligand for the leukocyte adhesion LFA-1 protein (Integrin alpha-L/beta-2) and a Rhinovirus receptor. Typically expressed on endothelial cells and cells of the immune system. ICAM1 binds to integrins of type CD11a / CD18, or CD11b / CD18. Its expression is activated by p53 in an NF-kappaB-independent manner. Induced by TNFalpha in a process that involves IKKbeta.
UniProt Protein Details:

Protein type:Cell adhesion; Membrane protein, integral; Immunoglobulin superfamily

Cellular Component: extracellular space; cell surface; focal adhesion; membrane; integral to plasma membrane; integral to membrane; plasma membrane; immunological synapse; external side of plasma membrane; lipid raft

Molecular Function:integrin binding; protein complex binding

Biological Process: regulation of cell adhesion; virion attachment, binding of host cell surface receptor; negative regulation of calcium ion transport; positive regulation of nitric oxide biosynthetic process; T cell antigen processing and presentation; activation of NF-kappaB transcription factor; positive regulation of cellular extravasation; regulation of cell shape; cell-cell adhesion; leukocyte adhesion; positive regulation of peptidyl-tyrosine phosphorylation; sensory perception of sound; positive regulation of actin filament polymerization; T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell; positive regulation of vasoconstriction; adhesion to host; cell adhesion mediated by integrin; cell adhesion; acute inflammatory response to antigenic stimulus

NCBI Summary:This gene encodes an integral membrane protein that binds leukocyte adhesion protein LFA-1. It participates in the innate immune response. [provided by RefSeq, Aug 2016]
UniProt Code:P13597
NCBI GenInfo Identifier:124099
NCBI Gene ID:15894
NCBI Accession:P13597.1
UniProt Related Accession:P13597
Molecular Weight:
NCBI Full Name:Intercellular adhesion molecule 1
NCBI Synonym Full Names:intercellular adhesion molecule 1
NCBI Official Symbol:Icam1  
NCBI Official Synonym Symbols:CD54; Ly-47; Icam-1; MALA-2  
NCBI Protein Information:intercellular adhesion molecule 1
UniProt Protein Name:Intercellular adhesion molecule 1
UniProt Synonym Protein Names:MALA-2; MyD10; CD_antigen: CD54
UniProt Gene Name:Icam1  
UniProt Entry Name:ICAM1_MOUSE

Related Products