Anti-ILF2 Antibody (CAB9530)
- SKU:
- CAB9530
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- NF45
- PRO3063
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
| Product Name: | ILF2 Rabbit mAb |
| Product Code: | CAB9530 |
| Size: | 20uL, 50uL, 100uL |
| Synonyms: | NF45, PRO3063 |
| Applications: | WB, IHC |
| Reactivity: | Human, Mouse, Rat |
| Host Species: | Rabbit |
| Immunogen: | A synthesized peptide derived from human ILF2 |
| Applications: | WB, IHC |
| Recommended Dilutions: | WB 1:500 - 1:2000 IHC 1:50 - 1:200 |
| Reactivity: | Human, Mouse, Rat |
| Positive Samples: | HeLa, HepG2, Raji, Mouse thymus, Rat testis |
| Immunogen: | A synthesized peptide derived from human ILF2 |
| Purification Method: | Affinity purification |
| Storage: | Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3. |
| Isotype: | IgG |
| Sequence: | Email for sequence |
| Gene ID: | 3608 |
| Uniprot: | Q12905 |
| Calculated MW: | 43kDa |
| Observed MW: | 43KDa |
| UniProt Protein Function: | ILF2: Appears to function predominantly as a heterodimeric complex with ILF3. This complex may regulate transcription of the IL2 gene during T-cell activation. It can also promote the formation of stable DNA-dependent protein kinase holoenzyme complexes on DNA. |
| UniProt Protein Details: | Protein type:RNA-binding; Transcription, coactivator/corepressor; Nucleolus Chromosomal Location of Human Ortholog: 1q21.3 Cellular Component: nucleoplasm; membrane; cytoplasm; nucleolus; ribonucleoprotein complex; nucleus Molecular Function:transferase activity; protein binding; DNA binding; double-stranded RNA binding; ATP binding Biological Process: transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; immune response |
| NCBI Summary: | The protein encoded by this gene is a transcription factor required for T-cell expression of the interleukin 2 gene. It also binds RNA and is an essential component for encapsidation and protein priming of hepatitis B viral polymerase. The encoded 45 kDa protein (NF45, ILF2) forms a complex with the 90 kDa interleukin enhancer-binding factor 3 (NF90, ILF3), and this complex has been shown to affect the redistribution of nuclear mRNA to the cytoplasm, to repair DNA breaks by nonhomologous end joining, and to negatively regulate the microRNA processing pathway. Knockdown of NF45 or NF90 protein retards cell growth, possibly by inhibition of mRNA stabilization. Alternative splicing results in multiple transcript variants. Related pseudogenes have been found on chromosomes 3 and 14. [provided by RefSeq, Dec 2014] |
| UniProt Code: | Q12905 |
| NCBI GenInfo Identifier: | 62510764 |
| NCBI Gene ID: | 3608 |
| NCBI Accession: | Q12905.2 |
| UniProt Secondary Accession: | Q12905,Q5SR10, Q5SR11, Q7L7R3, Q9BWD4, Q9P1N0, A6NDB0 B2R8G7, |
| UniProt Related Accession: | Q12905 |
| Molecular Weight: | 390 |
| NCBI Full Name: | Interleukin enhancer-binding factor 2 |
| NCBI Synonym Full Names: | interleukin enhancer binding factor 2 |
| NCBI Official Symbol: | ILF2Â Â |
| NCBI Official Synonym Symbols: | NF45; PRO3063Â Â |
| NCBI Protein Information: | interleukin enhancer-binding factor 2; interleukin enhancer binding factor 2, 45kD; nuclear factor of activated T-cells, 45-kDa; interleukin enhancer binding factor 2, 45kDa |
| UniProt Protein Name: | Interleukin enhancer-binding factor 2 |
| UniProt Synonym Protein Names: | Nuclear factor of activated T-cells 45 kDa |
| Protein Family: | Interleukin enhancer-binding factor |
| UniProt Gene Name: | ILF2Â Â |
| UniProt Entry Name: | ILF2_HUMAN |
Related Products
Human Anti-Apolipoprotein Antibody / AAHA ELISA Kit
€599
Human Anti-DSG3 antibody(anti-Desmoglein-3 antibody) ELISA Kit
€599
Mouse ACCPA / anti-cyclic citrullinated peptide antibody ELISA Kit
€649