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Key Features

LGI1 Rabbit Monoclonal Antibody (CAB19230)

Datasheet MSDS
SKU CAB19230
Product Type Antibody
Antibody Type Monoclonal Antibody
Reactivity Mouse, Rat
Host Species Rabbit
Synonyms EPT, ETL1, ADLTE, ADPAEF, ADPEAF, IB1099, EPITEMPIN, LGI1
Research Use Cell Biology
€131 - €457

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Description

system_update_altDatasheetsystem_update_altMSDS

LGI1 Monoclonal Antibody (CAB19230)

The LGI1 Monoclonal Antibody (CAB19230) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high specificity and reactivity with human samples, making it an ideal choice for Western blot applications. By targeting the LGI1 protein, this antibody enables accurate detection and analysis in various cell types, facilitating investigations in neurology and autoimmune disease research.

This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse, Rat samples.

Product Name:LGI1 Monoclonal Antibody
SKU:CAB19230
Size:20μL, 100μL
Reactivity:Mouse, Rat
Clone Number:ARC2388
Conjugate:Unconjugated
Immunogen:Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:NLQT LPKD IFKG LDSL TNVD LRGN SFNC DCKL KWLV EWLG HTNA TVED IYCE GPPE YKKR KINS LSSK DFDC IITE FAKS QDLP YQSL SIDT FSYL NDEY V
Tested Applications:WB ELISA
Recommended Dilution:
WB1:500 - 1:1000
ELISARecommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:EPT, ETL1, ADLTE, ADPAEF, ADPEAF, IB1099, EPITEMPIN, LGI1
Positive Sample:Mouse brain, Rat brain
Cellular Localization:Secreted, Synapse, Cytoplasm.
Calculated MW:64kDa
Observed MW:64kDa

This gene encodes a member of the secreted leucine-rich repeat (LRR) superfamily and shares homology with members of the SLIT protein family. The encoded protein may regulate the activity of voltage-gated potassium channels and may be involved in neuronal growth regulation and cell survival. This gene is rearranged as a result of translocations in glioblastoma cell lines, and it is frequently down-regulated or rearranged in malignant gliomas. Mutations in this gene result in autosomal dominant lateral temporal epilepsy. Alternative splicing results in multiple transcript variants.

Purification MethodAffinity purification
Gene ID9211
Buffer InformationStore at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol and 0.05% BSA, preserved with proclin300 or sodium azide, pH 7.3.
Product ImageWestern blot analysis of various lysates using LGI1 Rabbit mAb (CAB19230) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 90s.
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