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Anti-MOV10 Antibody (CAB7227)

SKU:
CAB7227
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
fSAP113
gb110
Research Area:
Immunology
€139 - €419
Frequently bought together:

Description

Product Name:MOV10 Rabbit mAb
Product Code:CAB7227
Size:20uL, 50uL, 100uL
Synonyms:fSAP113, gb110
Applications:WB
Reactivity:Human, Mouse, Rat
Host Species:Rabbit
Immunogen:A synthesized peptide derived from human MOV10
Applications:WB
Recommended Dilutions:WB 1:500 - 1:2000
Reactivity:Human, Mouse, Rat
Positive Samples:U2OS, HepG2, NIH/3T3, U-87MG, Mouse liver, Rat kidney
Immunogen:A synthesized peptide derived from human MOV10
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 0.05% BSA, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:4343
Uniprot:Q9HCE1
Cellular Location:Cytoplasm, P-body
Calculated MW:114kDa
Observed MW:114kDa
UniProt Protein Function:MOV10: Probable RNA helicase. Required for RNA-mediated gene silencing by the RNA-induced silencing complex (RISC). Required for both miRNA-mediated translational repression and miRNA- mediated cleavage of complementary mRNAs by RISC. Also required for RNA-directed transcription and replication of the human hepatitis delta virus (HDV). Interacts with small capped HDV RNAs derived from genomic hairpin structures that mark the initiation sites of RNA-dependent HDV RNA transcription. Belongs to the DNA2/NAM7 helicase family. SDE3 subfamily. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:RNA-binding; RNA processing; Helicase; EC 3.6.4.13; Spliceosome

Chromosomal Location of Human Ortholog: 1p13.2

Cellular Component: extracellular space; cytosol

Molecular Function:protein binding; helicase activity; ATP binding

Biological Process: epidermal growth factor receptor signaling pathway; Notch signaling pathway; fibroblast growth factor receptor signaling pathway; phosphoinositide-mediated signaling; transcription, DNA-dependent; regulation of transcription, DNA-dependent; nerve growth factor receptor signaling pathway; miRNA-mediated gene silencing, mRNA cleavage; innate immune response

UniProt Code:Q9HCE1
NCBI GenInfo Identifier:24638063
NCBI Gene ID:4343
NCBI Accession:Q9HCE1.2
UniProt Related Accession:Q9HCE1
Molecular Weight:
NCBI Full Name:Helicase MOV-10
NCBI Synonym Full Names:Mov10 RISC complex RNA helicase
NCBI Official Symbol:MOV10  
NCBI Official Synonym Symbols:gb110; fSAP113  
NCBI Protein Information:helicase MOV-10; putative helicase MOV-10
UniProt Protein Name:Putative helicase MOV-10
UniProt Synonym Protein Names:Moloney leukemia virus 10 protein
Protein Family:Putative helicase
UniProt Gene Name:MOV10  
UniProt Entry Name:MOV10_HUMAN

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