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Anti-Phospho-CGAS-S420 Antibody (CABP1228)

SKU:
CABP1228
Product type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Reactivity:
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
E330016A19Rik
Synonyms:
cGAS
€299 - €419
Frequently bought together:

Description

Product Name:Phospho-CGAS-S420 Rabbit pAb
Product Code:CABP1228
Size:50uL, 100uL
Synonyms:E330016A19Rik, cGAS
Applications:WB
Reactivity:Human, Rat
Host Species:Rabbit
Immunogen:A phospho synthetic peptide corresponding to residues surrounding S420 of Mouse CGAS.
Applications:WB
Recommended Dilutions:WB 1:500 - 1:2000
Reactivity:Human, Rat
Positive Samples:293T, C6
Immunogen:A phospho synthetic peptide corresponding to residues surrounding S420 of Mouse CGAS.
Purification Method:Affinity purification
Storage:Store at -20°C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Isotype:IgG
Sequence:Email for sequence
Gene ID:214763
Uniprot:Q8C6L5
Observed MW:62KDa
Background:The protein encoded by this gene is a DNA binding cytosolic protein that catalyzes the synthesis of cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) after sensing the presence of DNA in the cytoplasm. cGAMP binds another protein, Stimulator of interferon genes (STING), leading to the induction of interferons, and a host immune response. Reduced expression of this gene inhibits interferon induction in the presence of some viral infections. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

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