The Phospho-Tau-T181 Antibody (CABP1234) is a high-quality antibody developed for reliable detection and analysis of target proteins. Tau proteins play a crucial role in the formation of neurofibrillary tangles, a hallmark of neurodegenerative diseases like Alzheimer's. This antibody, generated in rabbits, specifically targets phosphorylated tau at the T181 site, enabling the detection and analysis of this important protein modification.Validated for use in Western blot applications, the Anti-Phospho-Tau (T181) Antibody (CABP1234) is highly reactive with human samples, providing researchers with a reliable tool for investigating tau pathology in neurological disorders.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human, Mouse samples.
Product Name:
Phospho-Tau-T181 Antibody
SKU:
CABP1234
Size:
20μL, 100μL
Reactivity:
Human, Mouse
Conjugate:
Unconjugated
Immunogen:
Synthetic peptide. This information is considered to be commercially sensitive.
Sequence:
PKTP P
Tested Applications:
WBELISA
Recommended Dilution:
WB
1:500 - 1:1000
ELISA
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. MAPT gene mutations have been associated with several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
Purification Method
Affinity purification
Gene ID
4137
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates, using Phospho-Tau-T181 Rabbit pAb (CABP1234) at 1:600 dilution. Mouse brain cells were treated by λ-PP mixed solution (1ul) at 30℃ for 30 minutes. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 30s.
