The SLFN11 Antibody (CAB20490) is a high-quality antibody developed for reliable detection and analysis of target proteins. This rabbit-derived antibody exhibits high reactivity with human samples and has been validated for use in Western blot applications.SLFN11, a member of the Schlafen family of proteins, has been shown to inhibit protein synthesis and promote cell death in response to DNA damage. Its presence has been correlated with increased sensitivity to certain cancer treatments, making it a promising target for further investigation in cancer research.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Human samples.
Product Name:
SLFN11 Antibody
SKU:
CAB20490
Size:
20μL, 100μL
Reactivity:
Human
Conjugate:
Unconjugated
Immunogen:
Recombinant protein (or fragment).This information is considered to be commercially sensitive.
Recommended starting concentration is 1 μg/mL. Please optimize the concentration based on your specific assay requirements.
Synonyms:
SLFN8/9, SLFN11
Positive Sample:
OVCAR3, DU145
Cellular Localization:
Cytosol, Nucleoplasm, Nucleus.
Calculated MW:
103kDa
Observed MW:
100kDa
Enables tRNA binding activity. Involved in several processes, including defense response to virus; negative regulation of G1/S transition of mitotic cell cycle; and replication fork arrest. Located in cytosol; nucleoplasm; and site of DNA damage.
Purification Method
Affinity purification
Gene ID
91607
Buffer Information
Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS containing 50% glycerol, preserved with proclin300 or sodium azide, pH 7.3.
Western blot analysis of various lysates using SLFN11 Rabbit pAb (CAB20490) at 1:1000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit (AbGn00020). Exposure time: 10s.
