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TET1 Monoclonal Antibody (CAB20833)

SKU:
CAB20833
Product Type:
Antibody
Antibody Type:
Secondary Antibody
Host Species:
Goat
Isotype:
Alexa Fluor 594 conjugated IgG
  • Immunohistochemistry of paraffin-embedded human testis using TET1 Rabbit mAb at dilution of 1:1600 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6. 0 before commencing with IHC staining protocol.
  • Immunohistochemistry of paraffin-embedded mouse testis using TET1 Rabbit mAb at dilution of 1:1600 (40x lens). Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6. 0 before commencing with IHC staining protocol.
  • Western blot analysis of extracts of ESCS cells, using TET1 antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
€179 - €469
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:TET1 Monoclonal Antibody
SKU:CAB20833
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 1749-1902 of mouse Tet1 (NP_001240786.1).
Sequence:HNTK SFSS ASST SHLV KDES TDFC PLQA SSAE TSTC TYSK TASG GFAE TSSI LHCT MPSG AHSG ANAA AGEC TGTV QPAE VAAH PHQS LPTA DSPV HAEP LTSP SEQL TSNQ SNQQ LPLL SNSQ KLAS CQVE DERH PEAD EPQH PEDD NLPQ LD
Tested Applications:IHC-P ELISA
Recommended Dilution:IHC-P,1:50 - 1:200
Synonyms:LCX; Cxxc6; mKIAA1676; D10Ertd17e; 2510010B09Rik; TET1
Positive Sample:Refer to figures
Conjugate:Unconjugated
Cellular Localization:nucleoplasm, nucleus
Calculated MW:219kDa
Observed MW:260kDa

Enables methylcytosine dioxygenase activity. Involved in several processes, including dendrite morphogenesis; inner cell mass cell differentiation; and protein O-linked glycosylation. Acts upstream of or within DNA demethylation; regulation of DNA methylation; and regulation of genetic imprinting. Located in nucleus. Is expressed in several structures, including brain; early conceptus; embryo ectoderm; lower urogenital tract; and reproductive system. Orthologous to human TET1 (tet methylcytosine dioxygenase 1).

Purification Method:Affinity purification
Gene ID:52463
Clone Number:ARC51466
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Product ImageImmunohistochemistry analysis of paraffin-embedded human testis using TET1 Rabbit mAb (CAB20833) at dilution of 1:100 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.

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