Description

APC Anti-Human CD133 Antibody [W6B3C1]

The CD133 Monoclonal Antibody (W6B3C1) offered by Assaygenie is a premium research tool designed for the detection and analysis of CD133, a key marker for cancer stem cells and progenitor cells. This high-quality antibody, derived through a monoclonal antibody production process, is specifically targeted for human samples and is ideal for a range of applications including immunofluorescence, flow cytometry, and immunohistochemistry.CD133, also known as prominin-1, is a transmembrane glycoprotein that has been linked to crucial functions in stem cell biology and tumorigenesis. Its expression is often associated with tumor-initiating cells in various types of cancers, making it a valuable target for cancer research and therapeutic development.

The CD133 Monoclonal Antibody (W6B3C1) provides researchers with a reliable tool for studying the role of CD133 in cancer progression, metastasis, and treatment resistance.By using this antibody, researchers can gain valuable insights into the presence and distribution of CD133 in different cellular contexts, facilitating a deeper understanding of its biological functions and potential clinical relevance. The CD133 Monoclonal Antibody (W6B3C1) from Assaygenie empowers researchers to advance their studies in oncology, regenerative medicine, and stem cell biology, offering a precise and sensitive tool for investigating the role of CD133 in health and disease.

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Product Title:	APC Anti-Human CD133 Antibody [W6B3C1]
SKU:	AGEL3044
Size:	20 Tests, 100 Tests, 200 Tests
Clone No:	W6B3C1
Synonyms:	Prominin-1;PROM1;AC133;PROML1;
Host Species:	Mouse
Reactivity:	Human
Application:	FCM

Isotype:	Mouse IgG1, κ
Isotype Control:	APC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:	Liquid
Conjugation:	APC
Recommended Use:	Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:

Swissprot:	O43490
Gene ID:	8842
Storage Buffer:	Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:	Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:	CD133, also known as Prominin-1 and AC133 antigen, is a 120 kD pentaspan glycoprotein with 5 transmembrane domains. CD133 was initially described as a surface antigen specific for human hematopoietic stem cells and as a marker for murine neuroepithelial cells and some embryonic epithelia. Later on, CD133 was found on other stem cells, including endothelial progenitor cells, glioblastomas, neuronal, and glial stem cells. In addition to stem cells for normal tissue, CD133 was found on cancer cells, such as some leukemia cells and brain tumor cells. Although the biological function of CD133 is not completely understood, CD133 has been extensively used as a stem cell marker for normal and cancerous tissues.

APC Anti-Human CD133 Antibody [W6B3C1] (AGEL3044)

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Description