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APC Anti-Human CD73 Antibody [AD2] (AGEL2490)

Datasheet MSDS
SKU AGEL2490
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Human
Host Species Mouse
Isotype Mouse IgG1, κ
Clone AD2
Conjugation APC
$174 - $644

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Description

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APC Anti-Human CD73 Antibody [AD2]

The APC Anti-Human CD73 Antibody (AD2) offered by Assay Genie is a powerful tool for researchers studying the CD73 cell surface molecule. CD73 plays a key role in immune regulation, particularly in the production of adenosine, which acts as a potent immunosuppressive molecule in the tumor microenvironment. This antibody, developed for use in flow cytometry and immunohistochemistry applications, is highly specific to human samples and enables the precise detection and analysis of CD73 expression in various cell types.CD73, also known as ecto-5'-nucleotidase, is involved in multiple biological processes, including inflammation, immune response modulation, and cancer progression.

By targeting CD73 with this antibody, researchers can explore its functions in immunology, oncology, and other fields, leading to a better understanding of its role in health and disease. The APC Anti-Human CD73 Antibody (AD2) holds great potential for advancing research in these areas and may contribute to the development of novel therapeutic strategies targeting CD73-mediated pathways.

Product Title:APC Anti-Human CD73 Antibody [AD2]
SKU:AGEL2490
Size:20 Tests, 100 Tests, 200 Tests
Clone No:AD2
Synonyms:Ecto-5'-nucleotidase; E.C3.1.3.5; L-VAP-2; NT5E; 5'-NT;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:APC Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P21589
Gene ID:4907
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD73 is a 70 kD glycophosphatidylinositol (GPI)-linked 5'-nucleotidase, which is also known as ecto-5'-nucleotidase. It converts adenosine monophosphate (AMP) to adenosine. CD73 is expressed on subsets of T and B cells, mesenchymal stem cells, follicular dendritic cells, endothelial cells, and epithelial cells. It has been reported that CD73 costimulates T cell activation, and mediates adhesion of lymphocytes to follicular dendritic cells and endothelial cells.
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