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PE/Cyanine7 Anti-Human CD73 Antibody [AD2] (AGEL3043)

Datasheet MSDS
SKU AGEL3043
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Human
Host Species Mouse
Isotype Mouse IgG1, κ
Clone AD2
Conjugation PE/Cyanine7
$162 - $702

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Description

system_update_altDatasheetsystem_update_altMSDS

PE/Cyanine7 Anti-Human CD73 Antibody [AD2]

The PE-Cyanine7 Anti-Human CD73 Antibody (AD2) available from AssayGenie is a high-quality antibody specifically designed for researchers studying CD73, an important cell surface enzyme involved in immune regulation and inflammation processes. This antibody, raised and validated for use in human samples, is ideal for flow cytometry applications, allowing for the precise detection and analysis of CD73 expression on various cell types.CD73, also known as ecto-5'-nucleotidase, plays a key role in adenosine production and the modulation of immune responses. Its expression has been linked to various physiological and pathological conditions, including cancer, inflammation, and immune disorders.

Understanding the role of CD73 in these processes is essential for developing targeted therapies and treatments that manipulate adenosine signaling pathways.By utilizing the PE-Cyanine7 Anti-Human CD73 Antibody (AD2) in research studies, scientists can gain valuable insights into the function and expression of CD73, paving the way for advancements in immunotherapy, cancer treatment, and the understanding of immune-related diseases. This antibody offers reliable results and reproducibility, making it a valuable tool for any laboratory conducting research in immunology, oncology, or related fields.

Product Title:PE/Cyanine7 Anti-Human CD73 Antibody [AD2]
SKU:AGEL3043
Size:20 Tests, 100 Tests, 200 Tests
Clone No:AD2
Synonyms:Ecto-5'-nucleotidase; E.C3.1.3.5; L-VAP-2; NT5E; 5'-NT;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PE/Cyanine7 Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PE/Cyanine 7
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P21589
Gene ID:4907
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD73 is a 70 kD glycophosphatidylinositol (GPI)-linked 5'-nucleotidase, which is also known as ecto-5'-nucleotidase. It converts adenosine monophosphate (AMP) to adenosine. CD73 is expressed on subsets of T and B cells, mesenchymal stem cells, follicular dendritic cells, endothelial cells, and epithelial cells. It has been reported that CD73 costimulates T cell activation, and mediates adhesion of lymphocytes to follicular dendritic cells and endothelial cells.
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