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PE Anti-Human CD73 Antibody [AD2] (AGEL2489)

Datasheet MSDS
SKU AGEL2489
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Human
Host Species Mouse
Isotype Mouse IgG1, κ
Clone AD2
Conjugation PE
€113 - €425

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Description

system_update_altDatasheetsystem_update_altMSDS

PE Anti-Human CD73 Antibody [AD2]

The PE Anti-Human CD73 Antibody (AD2) offered by Assay Genie is a highly specific and reliable tool for researchers working with CD73, a key cell surface marker implicated in various biological processes. The antibody is optimized for use in flow cytometry and immunofluorescence applications, enabling precise detection and analysis of CD73 expression in human samples.CD73, also known as ecto-5'-nucleotidase, plays a crucial role in purinergic signaling and immune regulation by catalyzing the conversion of AMP to adenosine. This enzymatic activity has significant implications in inflammation, cancer progression, and immune responses.

By targeting CD73 with this antibody, researchers can investigate its function in normal physiological processes and disease states, paving the way for potential therapeutic interventions.With its high specificity and sensitivity, the PE Anti-Human CD73 Antibody (AD2) from Assay Genie is an invaluable tool for studying the role of CD73 in immunology, oncology, and other research areas. Don't miss this opportunity to enhance your studies and unlock new insights into the intricate mechanisms governed by CD73.

Product Title:PE Anti-Human CD73 Antibody [AD2]
SKU:AGEL2489
Size:20 Tests, 100 Tests, 200 Tests
Clone No:AD2
Synonyms:Ecto-5'-nucleotidase; E.C3.1.3.5; L-VAP-2; NT5E; 5'-NT;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG1, κ
Isotype Control:PE Mouse IgG1, κ Isotype Control[MOPC-21]
Form:Liquid
Conjugation:PE
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P21589
Gene ID:4907
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD73 is a 70 kD glycophosphatidylinositol (GPI)-linked 5'-nucleotidase, which is also known as ecto-5'-nucleotidase. It converts adenosine monophosphate (AMP) to adenosine. CD73 is expressed on subsets of T and B cells, mesenchymal stem cells, follicular dendritic cells, endothelial cells, and epithelial cells. It has been reported that CD73 costimulates T cell activation, and mediates adhesion of lymphocytes to follicular dendritic cells and endothelial cells.
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