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APC Anti-Human CD20 Antibody [2H7] (AGEL2394)

Datasheet MSDS
SKU AGEL2394
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Human
Host Species Mouse
Isotype Mouse IgG2b, κ
Clone 2H7
Conjugation APC
$119 - $376

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Description

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APC Anti-Human CD20 Antibody [2H7]

The APC Anti-Human CD20 Antibody (2H7) offered by Assay Genie is a premium monoclonal antibody specifically designed for research applications involving CD20, a cell surface antigen widely expressed on B cells. This antibody, derived from mouse hybridoma, exhibits high specificity and sensitivity towards human CD20 protein, making it an excellent tool for a variety of immunological studies.CD20 is a crucial marker for B-cell identification and is involved in B-cell activation, differentiation, and proliferation. The APC Anti-Human CD20 Antibody (2H7) enables precise detection and visualization of CD20 in diverse cell types, facilitating detailed analysis in research areas such as immunology, oncology, and autoimmune diseases.

With its validated performance in flow cytometry and immunofluorescence applications, this antibody allows for accurate and reliable identification of CD20-expressing cells in experimental settings. Researchers can explore the role of CD20 in immune responses, B-cell disorders, and therapeutic interventions, enhancing our understanding of B-cell biology and disease mechanisms.Invest in the APC Anti-Human CD20 Antibody (2H7) from Assay Genie to elevate your research capabilities and gain valuable insights into the intricate functions of CD20 in human biology and disease pathology.

Product Title:APC Anti-Human CD20 Antibody [2H7]
SKU:AGEL2394
Size:20 Tests, 100 Tests, 200 Tests
Clone No:2H7
Synonyms:Bp35;Leukocyte surface antigen Leu-16;MS4A1;B-lymphocyte surface antigen B1;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2b, κ
Isotype Control:APC Mouse IgG2b, κ Isotype Control[MPC-11]
Form:Liquid
Conjugation:APC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P11836
Gene ID:931
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). It exists in a complex with MHC class I and II, CD53, CD81, and CD82.
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