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FITC Anti-Human CD20 Antibody [2H7] (AGEL2392)

Datasheet MSDS
SKU AGEL2392
Product Type Antibody
Antibody Type Monoclonal Antibody
Applications FCM
Reactivity Human
Host Species Mouse
Isotype Mouse IgG2b, κ
Clone 2H7
Conjugation FITC
€50 - €240

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Description

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FITC Anti-Human CD20 Antibody [2H7]

The FITC Anti-Human CD20 Antibody (2H7) is a cutting-edge tool designed for researchers studying CD20, a key protein expressed on the surface of B cells. This highly specific antibody, developed for use in flow cytometry applications, allows for the detection and analysis of CD20 in human samples with exceptional accuracy and sensitivity.CD20 is a well-known marker for B cells and plays a crucial role in various immune responses, including antibody production and autoimmune diseases. Targeting CD20 has been a successful strategy in treating B cell-related malignancies and autoimmune disorders. The FITC Anti-Human CD20 Antibody (2H7) provides researchers with a powerful tool to further investigate the function and expression of CD20 in different biological contexts.

By utilizing this antibody in their experiments, researchers can gain valuable insights into the role of CD20 in immune regulation, B cell development, and disease pathogenesis. Its high specificity and reliability make it an indispensable asset for studies in immunology, oncology, and autoimmune research. Explore the potential of the FITC Anti-Human CD20 Antibody (2H7) to advance your research and deepen our understanding of B cell biology and related disorders.

Product Title:FITC Anti-Human CD20 Antibody [2H7]
SKU:AGEL2392
Size:20 Tests, 100 Tests, 200 Tests
Clone No:2H7
Synonyms:Bp35;Leukocyte surface antigen Leu-16;MS4A1;B-lymphocyte surface antigen B1;
Host Species:Mouse
Reactivity:Human
Application:FCM
Isotype:Mouse IgG2b, κ
Isotype Control:FITC Mouse IgG2b, κ Isotype Control[MPC-11]
Form:Liquid
Conjugation:FITC
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
Spectrum:Spectrum Image
Swissprot:P11836
Gene ID:931
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD20 is a 33-37 kD, four transmembrane spanning protein, also known as B1 and Bp35. CD20 is expressed on pre-B-cells, resting and activated B cells (not plasma cells), some follicular dendritic cells, and at low levels on a T cell subset. CD20 is heavily phosphorylated on activated B cells and malignant B cells. Homo-oligomeric complexes of CD20 are thought to form Ca2+ conductive ion channels in the plasma membrane of B cells. The CD20 molecule is involved in B-cell activation and is associated with various Src family kinases (Lyn, Lck, Fyn). It exists in a complex with MHC class I and II, CD53, CD81, and CD82.
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